Eliasson Marie, Bastholm Pia, Forsberg Peter, Henriksson Kjell, Jacobson Lennart, Nilsson Anders, Gustafsson Lars L
Department of Drug Management and Informatics, Stockholm Health Region, Sweden.
Eur J Clin Pharmacol. 2006 Apr;62(4):251-8. doi: 10.1007/s00228-006-0114-2. Epub 2006 Mar 22.
To develop and verify proof of concept for a user-defined prescribing system with decision support based on one single database consisting of several pharmacological sources.
A multidisciplinary working group within the framework of a two-phase project developed the tool. A small-scale pilot study for proof of concept was carried out in an outpatient neurological polyclinic where four experienced physicians used the tool in patient care on a daily basis.
Automatically generated functions, such as recommended drugs, alerts for interactions, alerts for drug therapy during pregnancy and breast-feeding and a search tool for adverse drug effects, were quickly adopted into the daily outpatient working regime. Functions such as treatment strategies and a link to a producer independent website were less frequently used but still rated as useful and educational.
Searches for information that can be concentrated in one system saves time. Alerts inevitably draw physicians' attention to the information. Instant availability to drug recommendations in a computerised prescribing system such as Janus should increase adherence to recommendations, but this needs to be evaluated systematically. Small-scale pilot studies such as the one reported here have been shown to be invaluable in providing the theoretical basis for implementation of the system and for gaining an understanding of the complex change processes involved. Small-scale projects can therefore provided a base for further development and broader implementation of pharmacological tools and services.
基于包含多个药理学来源的单一数据库,开发并验证一个具有决策支持功能的用户自定义处方系统的概念验证。
在一个两阶段项目的框架内,一个多学科工作小组开发了该工具。在一家门诊神经科综合诊所进行了一项小规模的概念验证试点研究,四名经验丰富的医生在日常患者护理中使用该工具。
自动生成的功能,如推荐药物、相互作用警报、妊娠和哺乳期药物治疗警报以及药物不良反应搜索工具,很快被纳入门诊日常工作流程。治疗策略和与独立于生产商的网站的链接等功能使用频率较低,但仍被认为有用且具有教育意义。
在一个系统中集中搜索信息可节省时间。警报不可避免地会引起医生对这些信息的关注。在诸如Janus这样的计算机化处方系统中即时获得药物推荐应能提高对推荐的依从性,但这需要进行系统评估。像本文所报道的这样的小规模试点研究已被证明在为系统实施提供理论基础以及理解所涉及的复杂变革过程方面具有极高价值。因此,小规模项目可为药理学工具和服务的进一步开发及更广泛实施提供基础。