Geiger F, Schreiner K, Schneider S, Pauschert R, Thomsen M
Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstr. 200a, 69118, Heidelberg, Germany.
Orthopade. 2006 Jun;35(6):651-7. doi: 10.1007/s00132-006-0930-1.
In a retrospective study, 1.173 fractures of the proximal femur, which had been treated surgically, were analysed in two periods from 1975 to 1991 and from 1992 to 2000. The influence on mortality of preoperative risk factors and primary treatment with total hip replacement (THR), even in cases of pertrochanteric fractures, was analysed by stepwise logistic regression. In the later period, mortality within 90 days was 13.1%, and within 1 year 22.2%. Rejection of hemiendoprosthesis in high-risk patients with intracapsular fractures increased the mortality rate from 6.3% to 11.8%. The introduction of dynamic hip screws instead of Ender nails led to a reduction of mortality from 16.5 to 7.1%. Higher mortality after THR (27.6%) compared to osteosynthesis (15.5%) in pertrochanteric femur and lateral neck fractures was due to higher age and increased risk factors. Although the influence of some risk factors could be reduced, age, sex and morbidity influenced the outcome more than surgical treatment. THP, even after pertrochanteric fractures, is reasonable if it guarantees a quick and enduring mobilisation of the patient. Bicentric bipolar prostheses are recommended for high risk patients.
在一项回顾性研究中,对1975年至1991年以及1992年至2000年两个时间段内接受手术治疗的1173例股骨近端骨折进行了分析。通过逐步逻辑回归分析术前危险因素以及全髋关节置换术(THR)的初次治疗对死亡率的影响,即使是转子间骨折病例。在后期,90天内的死亡率为13.1%,1年内为22.2%。囊内骨折高危患者中半髋假体的排斥反应使死亡率从6.3%增加到11.8%。动力髋螺钉取代Ender钉导致死亡率从16.5%降至7.1%。转子间股骨和外侧颈骨折中,THR后的死亡率(27.6%)高于骨固定术(15.5%),这是由于年龄较大和危险因素增加。尽管一些危险因素的影响可以降低,但年龄、性别和发病率对结果的影响超过手术治疗。如果能保证患者快速且持久地活动,THP即使在转子间骨折后也是合理的。对于高危患者,推荐使用双中心双极假体。