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以轻度失语为表现的疱疹性脑炎:病例报告

Herpes encephalitis presenting as mild aphasia: case report.

作者信息

Khan Omar A, Ramsay Allan

机构信息

Department of Family Medicine, University of Vermont, Burlington, Vermont 05405, USA.

出版信息

BMC Fam Pract. 2006 Mar 24;7:22. doi: 10.1186/1471-2296-7-22.

Abstract

BACKGROUND

Encephalitis presenting as a change in mental status can be challenging to recognize in the primary care setting. However, early detection via a low threshold of suspicion can be useful, leading in turn to early treatment and improved survival.

CASE PRESENTATION

We present a case which we consider relevant to primary care practitioners. The patient in question presented with relatively mild mental status changes, progressing to confusion, dysnomia and delirium over a period of three days. While infection did not appear to be the leading cause on her differential diagnosis, she was found on extensive workup to have encephalitis caused by Herpes Simplex Virus type 1.

CONCLUSION

The case is instructive for general practitioners and other clinicians to maintain vigilance for central nervous system (CNS) infections which may present atypically.

摘要

背景

在基层医疗环境中,以精神状态改变为表现的脑炎可能难以识别。然而,通过低怀疑阈值进行早期检测可能有用,进而导致早期治疗并提高生存率。

病例介绍

我们呈现一个我们认为与基层医疗从业者相关的病例。该患者表现出相对轻微的精神状态改变,在三天内逐渐发展为意识模糊、命名障碍和谵妄。虽然感染在她的鉴别诊断中似乎不是主要原因,但在全面检查后发现她患有由1型单纯疱疹病毒引起的脑炎。

结论

该病例对全科医生和其他临床医生保持对可能非典型表现的中枢神经系统(CNS)感染的警惕具有指导意义。

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本文引用的文献

1
Herpes Simplex Encephalitis in Adults and Older Children.成人及大龄儿童的单纯疱疹性脑炎
Curr Treat Options Neurol. 2005 Mar;7(2):145-150. doi: 10.1007/s11940-005-0023-1.
4
Herpes simplex encephalitis: a review.单纯疱疹性脑炎:综述
Heart Lung. 1998 May-Jun;27(3):209-12. doi: 10.1016/s0147-9563(98)90009-7.
8
Viral encephalitis.病毒性脑炎
N Engl J Med. 1990 Jul 26;323(4):242-50. doi: 10.1056/NEJM199007263230406.

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