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比利时基于病房的临床药学服务的实施——对老年病房影响的描述

Implementation of ward-based clinical pharmacy services in Belgium--description of the impact on a geriatric unit.

作者信息

Spinewine Anne, Dhillon Soraya, Mallet Louise, Tulkens Paul M, Wilmotte Léon, Swine Christian

机构信息

School of Pharmacy, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Ann Pharmacother. 2006 Apr;40(4):720-8. doi: 10.1345/aph.1G515. Epub 2006 Mar 28.

Abstract

BACKGROUND

Patient-centered clinical pharmacy services are still poorly developed in Europe, despite their demonstrated advantages in North America and the UK. Reporting European pilot experiences is, therefore, important to assess the usefulness of clinical pharmacy services in this specific context.

OBJECTIVE

To report the results of the first implementation of Belgian clinical pharmacy services targeting patients at high risk of drug-related problems.

METHODS

An intervention study was conducted by a trained clinical pharmacist providing pharmaceutical care to 101 patients (mean age 82.2 y; mean +/- SD number of prescribed drugs 7.8 +/- 3.5) admitted to an acute geriatric unit, over a 7 month period. All interventions to optimize prescribing, and their acceptance, were recorded. An external panel (2 geriatricians, 1 clinical pharmacist) assessed the interventions' clinical significance. Persistence of interventions after discharge was assessed through telephone calls.

RESULTS

A total of 1066 interventions were made over the 7 month period. The most frequent drug-related problems underlying interventions were: underuse (15.9%), wrong dose (11.9%), inappropriate duration of therapy (9.7%), and inappropriate choice of medicine (9.6%). The most prevalent consequences were to discontinue a drug (24.5%), add a drug (18.6%), and change dosage (13.7%). Acceptance rate by physicians was 87.8%. Among interventions with clinical impact, 68.3% and 28.6% had moderate and major clinical significance, respectively. Persistence of chronic treatment changes 3 months after discharge was 84%.

CONCLUSIONS

Involving a trained clinical pharmacist in a geriatric team led to clinically relevant and well-accepted optimization of medicine use. This initiative may be a springboard for further development of clinical pharmacy services.

摘要

背景

以患者为中心的临床药学服务在欧洲仍发展不佳,尽管其在北美和英国已展现出优势。因此,报告欧洲的试点经验对于评估临床药学服务在这一特定背景下的实用性很重要。

目的

报告比利时针对有药物相关问题高风险患者开展的临床药学服务首次实施的结果。

方法

一项干预研究由一名经过培训的临床药师进行,该药师在7个月的时间里为入住急性老年科病房的101名患者(平均年龄82.2岁;平均±标准差,处方药物数量7.8±3.5种)提供药学服务。记录所有优化处方的干预措施及其接受情况。一个外部小组(2名老年病科医生、1名临床药师)评估干预措施的临床意义。出院后通过电话评估干预措施的持续性。

结果

在7个月期间共进行了1066次干预。干预措施背后最常见的药物相关问题是:用药不足(15.9%)、剂量错误(11.9%)、治疗持续时间不当(9.7%)以及药物选择不当(9.6%)。最常见的后果是停用一种药物(24.5%)、添加一种药物(18.6%)以及改变剂量(13.7%)。医生的接受率为87.8%。在具有临床影响的干预措施中,分别有68.3%和28.6%具有中度和重大临床意义。出院3个月后慢性治疗改变的持续性为84%。

结论

让一名经过培训的临床药师加入老年病科团队可实现临床上相关且得到广泛接受的用药优化。这一举措可能成为临床药学服务进一步发展的跳板。

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