Manios Yannis, Kafatos Anthony
Department of Nutrition & Dietetics, Harokopio University of Athens, Greece.
Br J Nutr. 2006 Mar;95(3):568-575. doi: 10.1079/bjn20051666.
The current study is a 4-year follow-up after the 6-year-long health and nutrition intervention programme applied in the primary schools of Crete. The aim of the current work was to identify whether the benefits obtained in certain health indices at the end of the intervention period were also present 4 years later. From a representative population of 441 pupils (250 from the intervention schools and 191 from the control schools), biochemical, dietary and physical activity data were obtained at baseline, at the end of the intervention period and after intervention (academic years 1992- 1993, 1997-1998 and 2001-2002, respectively). The findings of the current study revealed that the favourable changes in serum lipids observed at the end of the intervention period were maintained from baseline to after intervention for total cholesterol (-24-3 (SE 1.65) v. -9.70 (SE 2.03) mg/dl; P = 0-001), LDL-cholesterol(-18.6 (SE 1-41) v. -2.49 (SE 1.75) mg/dl; P < 0-001), HDL-cholesterol (-8-34 (SE 0.75) v. -9-60 (SE 1-10) mg/dl; P = 0-014) and total cholesterol :HDL-cholesterol ratio (0.31 (SE 0.06) v. 0.04 (SE 0.05); P = 0001). Similar favourable changes for the intervention group were observed in leisure-time physical activities (38.3 (SE 11-7) v. -13.2 (SE 10.9) min/week; P = 0.038) and BMI (6-05 (SE 0.18) v. 6.67 (SE 0-21) kg/m(2);P = 0.014), whereas no changes were observed in the fitness and dietary indices examined. The findings of the current study are encouraging, indicating maintenance of the favourable changes observed in serum lipids, BMI and physical activity 4 years after the programme had ended.
本研究是对克里特岛小学实施的为期6年的健康与营养干预计划进行的4年随访。当前这项工作的目的是确定在干预期结束时某些健康指标所获得的益处4年后是否依然存在。从441名学生(250名来自干预学校,191名来自对照学校)这一具有代表性的群体中,分别在基线期、干预期结束时以及干预后(分别为1992 - 1993学年、1997 - 1998学年和2001 - 2002学年)获取了生化、饮食和身体活动数据。当前研究结果显示,干预期结束时观察到的血清脂质的有利变化从基线期到干预后得以维持,总胆固醇(-24.3(标准误1.65)对 -9.70(标准误2.03)mg/dl;P = 0.001)、低密度脂蛋白胆固醇(-18.6(标准误1.41)对 -2.49(标准误1.75)mg/dl;P < 0.001)、高密度脂蛋白胆固醇(-8.34(标准误0.75)对 -9.60(标准误1.10)mg/dl;P = 0.014)以及总胆固醇与高密度脂蛋白胆固醇比值(0.31(标准误0.06)对0.04(标准误0.05);P = 0.001)。干预组在休闲时间身体活动(38.3(标准误11.7)对 -13.2(标准误10.9)分钟/周;P = 0.038)和体重指数(6.05(标准误0.18)对6.67(标准误0.21)kg/m²;P = 0.014)方面也观察到了类似的有利变化,而在所检查的体能和饮食指标方面未观察到变化。当前研究结果令人鼓舞,表明在该计划结束4年后,血清脂质、体重指数和身体活动方面观察到的有利变化得以维持。