Doroshenko A, Sherrard J, Pollard A J
University Department of Paediatrics, John Radcliffe Hospital, Oxford, UK.
Int J STD AIDS. 2006 Apr;17(4):221-7; quiz 228. doi: 10.1258/095646206776253354.
The recent increase in the number of cases of syphilis in the UK, including among women of reproductive age, has stimulated the need for a review of practices concerning assessment and management of syphilis in pregnancy and the neonatal period. This paper summarizes available evidence from published guidelines, primary and secondary research. Optimal management of syphilis in pregnancy and the neonatal period relies on the early diagnosis and staging of maternal disease, prompt treatment to prevent congenital syphilis, and timely assessment of newborns.
英国近期梅毒病例数量有所增加,包括育龄妇女中的病例,这促使人们有必要对妊娠和新生儿期梅毒的评估与管理做法进行审查。本文总结了已发表指南、一级和二级研究中的现有证据。妊娠和新生儿期梅毒的最佳管理依赖于对母体疾病的早期诊断和分期、预防先天性梅毒的及时治疗以及对新生儿的及时评估。