Ouhoummane Najwa, Levallois Patrick, Gingras Suzanne
Institut national de santé publique du Québec, Sainte-Foy (Quebec) Canada.
Arch Environ Health. 2004 Nov;59(11):582-7. doi: 10.1080/00039890409603437.
In this study, the authors compared thyroid function of newborns from 11 municipalities where drinking water was disinfected by chlorine dioxide (ClO2) with that of newborns from 15 municipalities using chlorine disinfection. They estimated the mean neonatal blood thyroid stimulating hormone (TSH) levels and proportion of congenital hypothyroidism cases using the results of the Quebec neonatal screening for congenital hypothyroidism for 32,978 newborns over the period 1993-1999. There was no significant increase in the TSH level and no excess of congenital hypothyroidism when all newborns exposed to ClO2 were considered. However, for newborns with low birth weight, mean TSH level was significantly higher among those exposed to ClO2 than for those in the reference group.
在本研究中，作者比较了来自11个使用二氧化氯（ClO₂）对饮用水进行消毒的城市的新生儿与来自15个使用氯消毒的城市的新生儿的甲状腺功能。他们利用1993年至1999年期间魁北克先天性甲状腺功能减退症新生儿筛查结果，估算了32978名新生儿的平均新生儿血促甲状腺激素（TSH）水平以及先天性甲状腺功能减退症病例的比例。当考虑所有接触ClO₂的新生儿时，TSH水平没有显著升高，也没有先天性甲状腺功能减退症的过量情况。然而，对于低出生体重的新生儿，接触ClO₂的新生儿的平均TSH水平显著高于参考组的新生儿。
