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[严重再生障碍性贫血异基因骨髓移植后足月正常妊娠:一例报告]

[Normal full-term pregnancy after allogeneic bone marrow transplantation for severe aplastic anemia: a case report].

作者信息

Kang B J, Tzeng C H, Chen L Y, Liu M, Fan S, Hsieh B K, Liu J H, Chiou T J, Chen P M

机构信息

Department of Medicine, Veterans General Hospital-Taipei.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 1991 Nov;48(5):404-7.

PMID:1659944
Abstract

A 27 year-old woman had a normal full-term delivery 4 years after bone narrow transplantation for severe aplastic anemia. She had received combination regimens of systemic high-dose cyclophosphamide and one fraction of total body irradiation for 300cGy as pre-BMT conditioning regimens. This case illustrates that after regimens incorporating total body irradiation and high-dose cyclophosphamide, recovery of ovarian function and normal pregnancy are still possible.

摘要

一名27岁女性在因严重再生障碍性贫血接受骨髓移植4年后足月顺产。她在骨髓移植前接受了全身大剂量环磷酰胺联合单次300cGy全身照射的预处理方案。该病例表明,在采用全身照射和大剂量环磷酰胺的方案后,卵巢功能仍有可能恢复并实现正常妊娠。

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