Solis O G, Bui H X, Malfetano J H, Ross J S
Department of Pathology and Laboratory Medicine, Albany Medical College, New York 12208.
Gynecol Oncol. 1991 Nov;43(2):182-5. doi: 10.1016/0090-8258(91)90069-h.
Malignant mixed mesodermal tumors (MMMT) are infrequent neoplasms characteristically arising in the endometrium. Extragenital MMMTs are extremely rare, with but 11 cases reported in the literature. Previous extragenital MMMTs have been associated with endometriosis, Wolfian duct remnants, and ovarian cyst adenocarcinoma and have been presumed to arise from coelomic and subcoelomic structures. We report a case of a MMMT arising extragenitally in the cul-de-sac in a 54-year-old White female patient in whom disseminated intraperitoneal serosal papillary serous adenocarcinoma of the peritoneum was present. The histogenesis of this rare neoplasm is discussed along with a brief review of previously reported cases.
恶性中胚叶混合瘤（MMMT）是一种罕见的肿瘤，典型地发生于子宫内膜。生殖器外的MMMT极为罕见，文献中仅报道过11例。既往生殖器外的MMMT与子宫内膜异位症、中肾管残余以及卵巢囊腺癌有关，据推测起源于体腔和体腔下结构。我们报告一例54岁白人女性患者，其生殖器外的MMMT发生于直肠子宫陷凹，同时存在腹膜播散性浆液性乳头状腺癌。本文讨论了这种罕见肿瘤的组织发生，并简要回顾了既往报道的病例。
