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Tigecycline (Tygacil): the first in the glycylcycline class of antibiotics.

作者信息

Greer Nickie D

机构信息

Department of Pharmacy Services, Baylor University Medical Center, Dallas, Texas, USA.

出版信息

Proc (Bayl Univ Med Cent). 2006 Apr;19(2):155-61. doi: 10.1080/08998280.2006.11928154.

DOI:10.1080/08998280.2006.11928154
PMID:16609746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1426172/
Abstract
摘要

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本文引用的文献

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Practice guidelines for the diagnosis and management of skin and soft-tissue infections.皮肤及软组织感染诊断和管理的实践指南。
Clin Infect Dis. 2005 Nov 15;41(10):1373-406. doi: 10.1086/497143. Epub 2005 Oct 14.
2
The efficacy and safety of tigecycline for the treatment of complicated intra-abdominal infections: analysis of pooled clinical trial data.替加环素治疗复杂性腹腔内感染的疗效和安全性：汇总临床试验数据分析
Clin Infect Dis. 2005 Sep 1;41 Suppl 5:S354-67. doi: 10.1086/431676.
3
The efficacy and safety of tigecycline in the treatment of skin and skin-structure infections: results of 2 double-blind phase 3 comparison studies with vancomycin-aztreonam.替加环素治疗皮肤及皮肤结构感染的疗效与安全性：两项与万古霉素-氨曲南对比的双盲3期研究结果
Clin Infect Dis. 2005 Sep 1;41 Suppl 5:S341-53. doi: 10.1086/431675.
4
Effects of age and sex on single-dose pharmacokinetics of tigecycline in healthy subjects.年龄和性别对健康受试者中替加环素单剂量药代动力学的影响。
Antimicrob Agents Chemother. 2005 Apr;49(4):1656-9. doi: 10.1128/AAC.49.4.1656-1659.2005.
5
Presence of tetracycline resistance determinants and susceptibility to tigecycline and minocycline.四环素耐药决定因素的存在以及对替加环素和米诺环素的敏感性。
Antimicrob Agents Chemother. 2005 Apr;49(4):1636-8. doi: 10.1128/AAC.49.4.1636-1638.2005.
6
Pharmacokinetic profile of tigecycline in serum and skin blister fluid of healthy subjects after multiple intravenous administrations.多次静脉给药后健康受试者血清和皮肤水疱液中替加环素的药代动力学特征。
Antimicrob Agents Chemother. 2005 Apr;49(4):1629-32. doi: 10.1128/AAC.49.4.1629-1632.2005.
7
Tigecycline: an investigational glycylcycline antimicrobial with activity against resistant gram-positive organisms.替加环素：一种正在研究的甘氨酰环素类抗菌药物，对耐药革兰氏阳性菌有活性。
Clin Ther. 2005 Jan;27(1):12-22. doi: 10.1016/j.clinthera.2005.01.007.
8
Tigecycline: clinical evidence and formulary positioning.替加环素：临床证据与处方集定位
Int J Antimicrob Agents. 2005 Mar;25(3):185-92. doi: 10.1016/j.ijantimicag.2004.11.006.
9
AcrAB efflux pump plays a role in decreased susceptibility to tigecycline in Morganella morganii.AcrAB外排泵在摩根氏摩根菌对替加环素敏感性降低中起作用。
Antimicrob Agents Chemother. 2005 Feb;49(2):791-3. doi: 10.1128/AAC.49.2.791-793.2005.
10
Pharmacokinetics of tigecycline after single and multiple doses in healthy subjects.健康受试者单次及多次给药后替加环素的药代动力学
Antimicrob Agents Chemother. 2005 Jan;49(1):220-9. doi: 10.1128/AAC.49.1.220-229.2005.