Sultana Yasmin, Jain R, Aqil M, Ali Asgar
Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, New Delhi 110062, India.
Curr Drug Deliv. 2006 Apr;3(2):207-17. doi: 10.2174/156720106776359186.
Successful treatment of eye diseases requires effective concentration of drug at the eye for sufficient period of time. Conventional ocular drug delivery including eye drops, systemic administration, ophthalmic ointments, is no longer sufficient to combat ocular diseases. This article reviews the constraints with conventional ocular therapy, and explores various novel approaches, to improve the ocular bioavailability of drugs to the anterior chamber of the eye.
成功治疗眼部疾病需要药物在眼部有效浓度维持足够长的时间。包括眼药水、全身给药、眼药膏在内的传统眼部给药方式，已不足以对抗眼部疾病。本文回顾了传统眼部治疗的局限性，并探索了各种新方法，以提高药物在前房的眼部生物利用度。
