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对5岁双胞胎问题行为教师评分的基因分析。

Genetic analyses of teacher ratings of problem behavior in 5-year-old twins.

作者信息

Polderman Tinca J C, Posthuma Daniëlle, De Sonneville Leo M J, Verhulst Frank C, Boomsma Dorret I

机构信息

Department of Biological Psychology, Vrije Universiteit of Amsterdam, Amsterdam, Netherlands.

出版信息

Twin Res Hum Genet. 2006 Feb;9(1):122-30. doi: 10.1375/183242706776402975.

Abstract

Behavioral problems in young children can be assessed by asking their parents or teachers to rate their behaviors. Genetic analyses of parental ratings show relatively large heritabilities for emotional and behavioral problems in young children, but data from teachers for this age group are scarce. Sources of variation in the Teacher's Report Form (TRF) problem scales were examined. The TRF was completed for 211 Dutch 5-year-old twin pairs and 4 single twins. Twins rated by different teachers had higher means and variances than twins rated by the same teacher, in addition twin correlations were lower in this group. In both groups monozygotic (MZ) correlations were generally higher than dizygotic (DZ) correlations. A model for twin resemblance was tested that allowed for these effects. For 5 problem scales (Withdrawn, Social Problems, Aggressive Behavior, Rule Breaking Behavior and Attention Problems) a model with genetic and unique environmental sources of variation fitted best to the data. For 3 problem scales (Anxious/Depressed, Thought Problems and Somatic Complaints) there were familial influences but it was not possible to distinguish between common environmental influences or genetic influences. Heritability was 63% for Attention problems, around 45% for Withdrawn, Social Problems, Aggressive Behavior and Rule Breaking Behavior, and around 30% for Anxious/Depressed, Thought Problems and Somatic Complaints.

摘要

幼儿的行为问题可以通过让其父母或老师对他们的行为进行评分来评估。对父母评分的基因分析表明,幼儿的情绪和行为问题具有相对较高的遗传度,但该年龄组教师提供的数据较少。研究了教师报告表(TRF)问题量表中的变异来源。对211对荷兰5岁双胞胎和4名单胞胎双胞胎完成了TRF。由不同教师评分的双胞胎比由同一名教师评分的双胞胎具有更高的均值和方差,此外,该组双胞胎的相关性更低。在两组中,同卵双胞胎(MZ)的相关性通常高于异卵双胞胎(DZ)的相关性。测试了一个考虑这些影响的双胞胎相似性模型。对于5个问题量表(退缩、社交问题、攻击行为、违规行为和注意力问题),一个具有遗传和独特环境变异来源的模型最适合这些数据。对于3个问题量表(焦虑/抑郁、思维问题和躯体不适)存在家族影响,但无法区分共同环境影响或遗传影响。注意力问题的遗传度为63%,退缩、社交问题、攻击行为和违规行为约为45%,焦虑/抑郁、思维问题和躯体不适约为30%。

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