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注射吸毒者中的艾滋病发病率和死亡率:巴西阿朱德二期项目

AIDS incidence and mortality in injecting drug users: the AjUDE-Brasil II Project.

作者信息

Cardoso Mauro Nogueira, Caiaffa Waleska Teixeira, Mingoti Sueli Aparecida

机构信息

Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

出版信息

Cad Saude Publica. 2006 Apr;22(4):827-37. doi: 10.1590/s0102-311x2006000400021. Epub 2006 Apr 5.

DOI:10.1590/s0102-311x2006000400021
PMID:16612436
Abstract

This paper presents AIDS incidence and mortality among injecting drug users (IDUs) reached by the AjUDE-Brasil II Project. From a cross-sectional survey, 478 IDUs were interviewed in three Brazilian cities: Porto Alegre, São José do Rio Preto, and Itajaí. The cohort was followed up in the Brazilian surveillance database for AIDS and mortality during 2000 and 2001. AIDS incidence was 1.1 cases per 100 person-years, and the mortality rate was 2.8 deaths per 100 person-years. AIDS cases only occurred in IDUs who reported ever having shared injecting equipment. Female gender (RR = 5.30), homelessness (RR = 6.16), and report of previous sexual relations with same-sex partners (RR = 6.21) were associated with AIDS. Deaths occurred only among males. Homelessness (RR = 3.00), lack of income (RR = 2.65), HIV seropositive status (RR = 4.52), and no history of incarceration (RR = 3.71) were also associated with death. These findings support evidence that gender and socioeconomic conditions are both determinants of morbidity and mortality in Brazilian IDUs.

摘要

本文介绍了巴西艾滋病防治项目二期(AjUDE-Brasil II Project)所覆盖的注射吸毒者(IDUs)中的艾滋病发病率和死亡率。通过一项横断面调查,在巴西的三个城市——阿雷格里港、里约普雷图河畔圣若泽和伊塔雅伊,对478名注射吸毒者进行了访谈。在2000年至2001年期间,对该队列在巴西艾滋病和死亡率监测数据库中进行了随访。艾滋病发病率为每100人年1.1例,死亡率为每100人年2.8例。艾滋病病例仅发生在报告曾共用注射器具的注射吸毒者中。女性(相对危险度=5.30)、无家可归(相对危险度=6.16)以及报告曾与同性伴侣发生性关系(相对危险度=6.21)与艾滋病相关。死亡仅发生在男性中。无家可归(相对危险度=3.00)、缺乏收入(相对危险度=2.65)、HIV血清学阳性状态(相对危险度=4.52)以及无监禁史(相对危险度=3.71)也与死亡相关。这些发现支持了以下证据,即性别和社会经济状况都是巴西注射吸毒者发病和死亡的决定因素。

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