Holme J Bendix, Nielsen D Tønner, Funch-Jensen P, Mortensen F Viborg
Department of Surgery L, Aarhus University Hospital, Aarhus, Denmark.
Acta Radiol. 2006 Apr;47(3):244-7. doi: 10.1080/02841850600550690.
To evaluate the efficacy and safety of transcatheter arterial embolization (TAE) in patients with bleeding/rebleeding duodenal ulcers.
Over a 6-year-period, 40 consecutive patients with bleeding/ rebleeding after endoscopic therapy and/or surgery for duodenal ulcer were included in the study. Superselective angiographic catheterization and coil embolization were performed by the same interventional radiologist.
Lasting hemostasis was achieved in 26 of 40 patients (65%). Transfusion requirement was reduced from median 14 (range 3-35) units of blood before TAE to 2 (range 0-53) units after TAE. Ten patients died, five because of continuous bleeding. No adverse effects as a result of TAE were seen.
TAE is an effective and safe treatment in a significant proportion of patients with bleeding duodenal/rebleeding ulcers after therapeutic endoscopy and/or surgery.
评估经导管动脉栓塞术（TAE）治疗十二指肠溃疡出血/再出血患者的疗效和安全性。
在6年期间，本研究纳入了40例因十二指肠溃疡接受内镜治疗和/或手术后出现出血/再出血的连续患者。由同一位介入放射科医生进行超选择性血管造影插管和弹簧圈栓塞术。
40例患者中有26例（65%）实现了持久止血。输血需求量从TAE前的中位数14（范围3 - 35）单位血液降至TAE后的2（范围0 - 53）单位。10例患者死亡，5例死于持续出血。未观察到TAE引起的不良反应。
对于相当一部分经治疗性内镜检查和/或手术后出现十二指肠溃疡出血/再出血的患者，TAE是一种有效且安全的治疗方法。
