未破裂颅内动脉瘤的血管内治疗
Endovascular management of unruptured intracranial aneurysms.
作者信息
Pouratian N, Oskouian R J, Jensen M E, Kassell N F, Dumont A S
机构信息
University of Virginia, Department of Neurological Surgery, Box 800212, Charlottesville, VA 22903, USA.
出版信息
J Neurol Neurosurg Psychiatry. 2006 May;77(5):572-8. doi: 10.1136/jnnp.2005.078469.
Abstract
Endovascular coil embolisation is increasingly used to treat unruptured intracranial aneurysms (UIA). Endovascular coil embolisation of UIA is associated with a 5-10% risk of morbidity and nearly zero mortality from the procedure. Complete or near complete occlusion is usually achieved in >90% of cases, and endovascular therapy seems to reduce the risk of future rupture significantly. Specific selection criteria for endovascular embolisation and novel approaches to endovascular treatment of aneurysms are discussed. Endovascular therapy appears to be a safe and effective treatment for selected UIA. Treatment failure rates will probably decrease with greater experience and advances in techniques and devices. Further study with long term follow up, however, is still necessary to characterise the efficacy, durability, and cost efficiency of endovascular treatment of UIA.
摘要
血管内弹簧圈栓塞术越来越多地用于治疗未破裂颅内动脉瘤（UIA）。UIA的血管内弹簧圈栓塞术有5% - 10%的发病风险，且该手术的死亡率几乎为零。在超过90%的病例中通常可实现完全或接近完全闭塞，并且血管内治疗似乎能显著降低未来破裂的风险。文中讨论了血管内栓塞的具体选择标准以及动脉瘤血管内治疗的新方法。血管内治疗对于选定的UIA似乎是一种安全有效的治疗方法。随着经验的增加以及技术和设备的进步，治疗失败率可能会降低。然而，仍需要进行长期随访的进一步研究，以明确UIA血管内治疗的疗效、持久性和成本效益。
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