Michelozzi Paola, De Sario Manuela, Accetta Gabriele, de'Donato Francesca, Kirchmayer Ursula, D'Ovidio Mariangela, Perucci Carlo A
Department of Epidemiology, Local Health Authority RM/E, Via di Santa Costanza 53, Rome 00198, Italy.
J Epidemiol Community Health. 2006 May;60(5):417-23. doi: 10.1136/jech.2005.040857.
To investigate geographical and temporal variations in the temperature-mortality relation.
The relation between mortality and maximum apparent temperature (Tappmax) in 2003, 2004, and a previous reference period was explored by using segmented regression and generalised additive models.
Four Italian cities (Bologna, Milano, Roma, and Torino), included in a national network of prevention programmes and heat health watch warning systems (HHWWS) were considered.
Daily mortality counts of the resident population dying in each city during summer (June to September).
The impact of Tappmax on mortality differed between cities and varied in the three periods analysed. The geographical heterogeneity of the J shaped relation was seen in the reference period with Tappmax thresholds ranging from 28 degrees C in Torino to 32 degrees C in Milano and Roma. In all cities, the percentage variation in mortality was greatest in 2003. In Torino and Roma a significant increase was seen also at lower Tappmax values that are usually not associated to an increase in mortality (26-28 degrees C). In summer 2004 the exposure levels were similar to the reference period; only in Torino the effect of Tappmax on mortality remained relevant even if reduced compared with 2003, while in Bologna no statistically significant effect was seen for any temperature range.
The observed heterogeneous reduction in the impact of temperature on mortality from 2003 to 2004 may be partly explained by the lower levels of exposure. Changes in the ability of individuals and communities to adjust to high temperatures as a consequence of the implementation of public health interventions, based on HHWWS, characterised by a diverse effectiveness, may also have played an important part.
调查温度与死亡率关系中的地理和时间变化。
通过使用分段回归和广义相加模型,探讨了2003年、2004年以及之前参考期内死亡率与最高表观温度(Tappmax)之间的关系。
考虑了四个意大利城市(博洛尼亚、米兰、罗马和都灵),这些城市纳入了国家预防计划和热健康监测预警系统(HHWWS)网络。
夏季(6月至9月)每个城市常住居民的每日死亡人数。
Tappmax对死亡率的影响在不同城市之间存在差异,并且在分析的三个时期有所不同。在参考期内观察到J形关系的地理异质性,Tappmax阈值范围从都灵的28摄氏度到米兰和罗马的32摄氏度。在所有城市中,2003年死亡率的百分比变化最大。在都灵和罗马,在通常与死亡率增加无关的较低Tappmax值(26 - 28摄氏度)时也观察到显著增加。2004年夏季的暴露水平与参考期相似;只有在都灵,Tappmax对死亡率的影响即使与2003年相比有所降低但仍然显著,而在博洛尼亚,在任何温度范围内均未观察到统计学上的显著影响。
2003年至2004年期间观察到的温度对死亡率影响的异质性降低可能部分归因于较低的暴露水平。基于HHWWS实施的公共卫生干预措施具有不同的有效性,个人和社区适应高温能力的变化也可能起到了重要作用。