Kim Tae Bum, Kim Yoon Keun, Chang Yoon Seok, Kim Sang Hoon, Hong Sung Chul, Jee Young Koo, Cho Sang Heon, Min Kyung Up, Kim You Young
Department of Internal Medicine, Seoul National University College of Medicine, Yongon-dong, Chongno-gu, Korea.
J Korean Med Sci. 2006 Apr;21(2):247-52. doi: 10.3346/jkms.2006.21.2.247.
It has been demonstrated that spider mites such as the two-spotted spider mite (Tetranychus urticae) are important allergens for fruit farmers. A total of 2,467 adults (795 metropolitan urban, 788 non-metropolitan urban, and 884 rural subjects) were enrolled. They responded to the questionnaire, and underwent methacholine bronchial provocation tests as well as skin prick tests to locally common aeroallergens including the two-spotted spider mite. The prevalences of asthma and rhinitis as reported on the questionnaire were 7.8% and 16.4% of adults aged 20-35, 9.4% and 24.7% of those 36-50, and 17.7% and 21.7% of those older than 50, respectively. Among the older group, the two-spotted spider mite was the most common sensitizing allergen, although it was second of that of house dust mites among the other two age groups. Sensitization to the two-spotted spider mite was significantly associated with the prevalence of asthma and rhinitis among the younger age group, and associated with the prevalence of rhinitis among the older age group. The two-spotted spider mite might be a common sensitizing allergen in the general population of adults, and sensitization to this mite may play a role in the manifestation of asthma and rhinitis symptoms during adulthood.
已证实，叶螨，如二斑叶螨（Tetranychus urticae），是果农的重要过敏原。总共招募了2467名成年人（795名大城市城市居民、788名非大城市城市居民和884名农村受试者）。他们回答了问卷，并接受了乙酰甲胆碱支气管激发试验以及针对包括二斑叶螨在内的当地常见气传过敏原的皮肤点刺试验。问卷中报告的哮喘和鼻炎患病率在20 - 35岁成年人中分别为7.8%和16.4%，在36 - 50岁人群中分别为9.4%和24.7%，在50岁以上人群中分别为17.7%和21.7%。在年龄较大的组中，二斑叶螨是最常见的致敏过敏原，尽管在其他两个年龄组中它是仅次于屋尘螨的过敏原。对二斑叶螨的致敏与较年轻年龄组中哮喘和鼻炎的患病率显著相关，并且与年龄较大组中鼻炎的患病率相关。二斑叶螨可能是成年普通人群中一种常见的致敏过敏原，对这种螨的致敏可能在成年期哮喘和鼻炎症状的表现中起作用。
