Park In Sung, Han Jong Woo, Lee Kea Joo, Lee Nam Joon, Lee Won Teak, Park Kyung Ah, Rhyu Im Joo
Department of Anatomy, College of Medicine, Korea University, Sungbuk-gu, Seoul, Korea.
J Korean Med Sci. 2006 Apr;21(2):342-6. doi: 10.3346/jkms.2006.21.2.342.
Cerebellum is a key structure involved in motor learning and coordination. In animal models, motor skill learning increased the volume of molecular layer and the number of synapses on Purkinje cells in the cerebellar cortex. The aim of this study is to investigate whether the analogous change of cerebellar volume occurs in human population who learn specialized motor skills and practice them intensively for a long time. Magnetic resonance image (MRI)-based cerebellar volumetry was performed in basketball players and matched controls with V-works image software. Total brain volume, absolute and relative cerebellar volumes were compared between two groups. There was no significant group difference in the total brain volume, the absolute and the relative cerebellar volume. Thus we could not detect structural change in the cerebellum of this athlete group in the macroscopic level.
小脑是参与运动学习和协调的关键结构。在动物模型中，运动技能学习增加了分子层的体积以及小脑皮质浦肯野细胞上突触的数量。本研究的目的是调查在长期密集学习和练习专门运动技能的人群中，小脑体积是否会发生类似变化。使用V-works图像软件对篮球运动员和匹配的对照组进行基于磁共振成像（MRI）的小脑容积测量。比较两组之间的全脑体积、绝对和相对小脑体积。两组在全脑体积、绝对和相对小脑体积方面没有显著差异。因此，我们在宏观水平上未检测到该运动员组小脑的结构变化。
