Swinkels Sophie H N, Dietz Claudine, van Daalen Emma, Kerkhof Ine H G M, van Engeland Herman, Buitelaar Jan K
Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, B01.201, Post Box 85500, 3508, GA, Utrecht, The Netherlands.
J Autism Dev Disord. 2006 Aug;36(6):723-32. doi: 10.1007/s10803-006-0115-0.
This article describes the development of a screening instrument for young children. Screening items were tested first in a non-selected population of children aged 8-20 months (n = 478). Then, parents of children with clinically diagnosed ASD (n = 153, average age 87 months) or ADHD (n = 76, average age 112 months) were asked to score the items retrospectively for when their child was 14 months old. A 14-item screening instrument, Early Screening of Autistic Traits (ESAT) which had maximal sensitivity and specificity for ASD was developed. The sensitivity of the ESAT was checked in an independent sample of 34 children aged 16-48 months clinically diagnosed with ASD. A 4-item version appears to be a promising prescreening instrument.
本文描述了一种针对幼儿的筛查工具的开发过程。筛查项目首先在8至20个月大的未经过挑选的儿童群体(n = 478)中进行测试。然后,临床诊断为自闭症谱系障碍(ASD,n = 153,平均年龄87个月)或注意力缺陷多动障碍(ADHD,n = 76,平均年龄112个月)儿童的家长被要求回顾性地对其孩子14个月大时的项目进行评分。开发出了一种包含14个项目的筛查工具——自闭症特征早期筛查(ESAT),它对ASD具有最大的敏感性和特异性。在一个由34名临床诊断为ASD的16至48个月大儿童组成的独立样本中检查了ESAT的敏感性。一个包含4个项目的版本似乎是一种有前景的预筛查工具。