Coulibaly M, Noba V, Rey J-L, Msellati P, Ekpini R, Chambon J-F, Malkin J-E
ESTHER (Ensemble pour une solidarité thérapeutique hospitalière en réseau) 36, rue de Charenton, 75015 Paris.
Med Trop (Mars). 2006 Feb;66(1):53-8.
The purpose of this article is to report the results of a programme for prevention of mother-to-child transmission (PMCT) of HIV conducted from 1999 to 2002 by the PNLS in Abidjan, Ivory Coast. This programme was supported by grants from the Fonds de solidarité international (FSTI) and the Glaxo Smith Kline (GSK) Foundation. After pre- and posttest counselling, pregnant women from 4 PMI centres underwent screening for HIV. Seropositive women were offered short course AZT and the possibility of financial assistance for breast-feeding. All programme activities were carried out in close cooperation with association members. A total of 22466 tests were given and 18116 women returned for results. Among the 1829 seropositive women to whom PMCT intervention was proposed, 667 received short course AZT. The rate of transmission at 18 months was 162%. In addition 69 mothers and 28 children eligible for ARV therapy benefited from tritherapy. Limiting factors, at each phase, and efficacy of intervention were analyzed.
本文旨在报告1999年至2002年期间，由位于科特迪瓦阿比让的国家艾滋病防治计划（PNLS）开展的预防艾滋病母婴传播（PMCT）项目的结果。该项目由国际团结基金（FSTI）和葛兰素史克（GSK）基金会提供资助。在进行前后测试咨询后，来自4个预防母婴传播中心的孕妇接受了艾滋病毒筛查。血清反应呈阳性的妇女接受了短期齐多夫定治疗，并有可能获得母乳喂养的经济援助。所有项目活动均与协会成员密切合作开展。共进行了22466次检测，18116名妇女返回获取检测结果。在1829名被建议接受预防母婴传播干预的血清反应呈阳性妇女中，667人接受了短期齐多夫定治疗。18个月时的传播率为162%。此外，69名母亲和28名符合抗逆转录病毒疗法条件的儿童受益于三联疗法。分析了每个阶段的限制因素和干预效果。
