La Marca Antonio, Pati Mariangela, Orvieto Raoul, Stabile Gaspare, Carducci Artenisio Alfredo, Volpe Annibale
Mother-Infant Department, Institute of Obstetrics and Gynecology, University of Modena and Reggio Emilia, Modena, Italy.
Fertil Steril. 2006 May;85(5):1547-9. doi: 10.1016/j.fertnstert.2005.10.057. Epub 2006 Apr 17.
Anti-müllerian hormone (AMH) appears to regulate follicular growth. The aim of this study was to investigate AMH serum levels in patients affected by secondary amenorrhea. The AMH was significantly lower (or undetectable) in patients with premature ovarian failure (POF) and significantly higher in patients affected by polycystic ovary syndrome (PCOS). We suggest that serum AMH evaluation could be associated with that of established hormones, such as FSH, LH, and E2, when the activity of hypothalamo-pituitary-ovarian axis is investigated.
抗苗勒管激素（AMH）似乎对卵泡生长具有调节作用。本研究旨在调查继发性闭经患者的血清AMH水平。卵巢早衰（POF）患者的AMH水平显著降低（或检测不到），而多囊卵巢综合征（PCOS）患者的AMH水平则显著升高。我们建议，在研究下丘脑-垂体-卵巢轴的活性时，血清AMH评估可与FSH、LH和E2等已确定的激素评估相结合。
