Lund Vera, Børdal Susanna, Kjellsen Ole, Mikkelsen Helene, Schrøder Merete B
Fiskeriforskning, Norwegian Institute of Fisheries and Aquaculture Research, N-9291 Tromsø, Norway.
Dev Comp Immunol. 2006;30(12):1145-55. doi: 10.1016/j.dci.2006.02.004. Epub 2006 Mar 23.
The immune system of Atlantic cod (Gadus morhua L.) differ from other bony fish species in that no or only very low increases in antibody levels are detected post-immunization with Vibrio salmonicida or V. anguillarum. Here, we report the results from the first study on comparison of antibody responses in cod to Aeromonas salmonicida and V. anguillarum. A. salmonicida appear to induce a stronger antibody response in cod compared to V. anguillarum, and more individuals immunized with A. salmonicida revealed a response compared to those immunized with V. anguillarum. The antibody responses to both bacterial species were mainly toward LPS, and the results indicate that cod antibodies are able to differentiate between LPS antigens from typical and atypical A. salmonicida strains.
大西洋鳕鱼（Gadus morhua L.）的免疫系统与其他硬骨鱼类不同，在于用杀鲑气单胞菌或鳗弧菌免疫后，未检测到抗体水平升高或仅检测到非常低的升高。在此，我们报告了第一项关于鳕鱼对杀鲑气单胞菌和鳗弧菌抗体反应比较研究的结果。与鳗弧菌相比，杀鲑气单胞菌似乎在鳕鱼中诱导更强的抗体反应，并且与用鳗弧菌免疫的个体相比，更多用杀鲑气单胞菌免疫的个体表现出反应。对这两种细菌的抗体反应主要针对脂多糖，结果表明鳕鱼抗体能够区分典型和非典型杀鲑气单胞菌菌株的脂多糖抗原。
