García-Prats M D, Sotelo-Rodríguez M T, Ballestín C, Martínez-González M A, Roca R, Alfaro J, De Miguel E
Department of Pathology, Hospital 12 de Octubre, Madrid, Spain.
Histopathology. 1991 Nov;19(5):459-64. doi: 10.1111/j.1365-2559.1991.tb00237.x.
A case of glomus tumour of the trachea is reported. The patient, a 58-year-old man, complained of dyspnoea, cough and occasional haemoptysis for many years and had been misdiagnosed as having chronic bronchitis. The diagnosis of glomus tumour in a tissue sample taken by bronchoscopy was useful in planning adequate surgery. Light and electromicroscopy of the excised tumour confirmed the preoperative diagnosis. Immunohistochemical examination showed vimentin and actin in the tumour cells, and negativity for high and low molecular weight keratins, desmin, neurofilaments, and factor VIII-related antigen, findings similar to glomus tumours of other sites.
报告了一例气管球瘤病例。患者为一名58岁男性，多年来一直主诉呼吸困难、咳嗽及偶尔咯血，曾被误诊为慢性支气管炎。通过支气管镜采集的组织样本诊断为球瘤，这对规划适当的手术很有帮助。切除肿瘤的光镜和电镜检查证实了术前诊断。免疫组化检查显示肿瘤细胞中有波形蛋白和肌动蛋白，高分子量和低分子量角蛋白、结蛋白、神经丝和因子VIII相关抗原均为阴性，这些结果与其他部位的球瘤相似。
