Crochet Sylvain, Petersen Carl C H
Laboratory of Sensory Processing, Brain Mind Institute, SV-BMI-LSENS AAB 105, Station 15, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
Nat Neurosci. 2006 May;9(5):608-10. doi: 10.1038/nn1690. Epub 2006 Apr 16.
To investigate synaptic events underlying sensory perception, we made whole-cell membrane potential recordings of barrel cortex neurons in awake mice while recording whisker-related behavior. During quiet periods, we recorded slow, large-amplitude membrane potential changes, which switched during whisking to small, fast fluctuations that were correlated with whisker position. Robust subthreshold responses were evoked by passive whisker stimulation during quiet behavior and by active whisker contact with an object.
为了研究感觉知觉背后的突触事件，我们在记录清醒小鼠触须相关行为的同时，对其桶状皮层神经元进行了全细胞膜电位记录。在安静时期，我们记录到缓慢、大幅度的膜电位变化，在触须运动时这些变化转变为与触须位置相关的小而快速的波动。在安静行为期间，被动触须刺激以及主动触须与物体接触均可诱发强烈的阈下反应。
