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实际年龄会降低工作能力吗?

Does chronological age reduce working ability?

作者信息

Duraković Zijad, Misigoj-Duraković Marjeta

机构信息

Department of Internal Medicine, University Hospital Center "Zagreb", School of Medicine, University of Zagreb, Croatia.

出版信息

Coll Antropol. 2006 Mar;30(1):213-9.

Abstract

Definitions of so-called older age often are based on a chronological age of 65 years and over, although by some authors aging is the process that starts after the 30th year of life. At the beginning occur changes in the organ functions, followed by anatomical changes as well. Some organs age faster, some slower. For example, kidneys decrease for one third, lungs do not change, liver shrinks a little, prostate increases twice. In some cross-sectional studies, muscle mass in men aged 65 is on average 12 kg less than in the so-called middle age, and in women it is approximately 5 kg less. In the heart the amount of connective tissue increases, lipofuscin is deposited in cardiac muscle, the strength of which is decreasing. In the respiratory tract the number of pathways cilia decreases, along with the alveolar surface, muscles involved in breathing change, lung elasticity is also diminished. But, in regard with the previous body capacity, "physiological aging" can be divided into three types of elderly: the "older" elderly have the highest functional capacity of 2-3 MET (MET--metabolic unit, i.e. the oxygen consumption of 3.5 ml/kg body mass in a minute), the "younger" elderly are the persons of older age having maximal functional capacity of 5-7 MET, while the "sport" elderly have the functional capacity of 9-10 MET, disregarding chronological age. The brain weight diminishes for approximately 7% compared to younger age. In temporal gyrus and area striata even 20-40% of cells are being lost, vacuolar and neuroaxonal degeneration occurs, lipofuscin is being accumulated. The brain blood flow, which is in normal conditions 50-60 ml/min/100 g of tissue, with the increase of biological age decreases to about 40 ml/min/100 g of tissue. However, this usually is not the consequence of biological age but of disease. A chronological age of 65 for the beginning of "elder hood" is a sociopolitical construct developed by social security systems and government organizations to decide an arbitrary age at which benefits should be paid. Thus, it neither a border nor do changes designating old age occurs exactly with that "age border". The changes in the organism during the so-called aging are individual. So, the functional capacity of an organism, both physical and intellectual, must be evaluated individually, having in mind biological age.

摘要

所谓老年的定义通常基于65岁及以上的实足年龄,不过有些作者认为衰老过程始于30岁以后。首先出现器官功能变化,随后也会发生解剖结构变化。有些器官衰老得快,有些则慢。例如,肾脏功能下降三分之一,肺功能不变,肝脏略有萎缩,前列腺增大两倍。在一些横断面研究中,65岁男性的肌肉量平均比所谓中年男性少12千克,女性则少约5千克。心脏中结缔组织增多,脂褐素沉积在心肌中,心肌力量减弱。呼吸道中纤毛数量减少,肺泡表面积减小,参与呼吸的肌肉发生变化,肺弹性也降低。但是,就之前的身体能力而言,“生理衰老”可分为三种类型的老年人:“高龄”老年人的最高功能能力为2 - 3代谢当量(MET——代谢单位,即每分钟每千克体重耗氧量3.5毫升),“低龄”老年人是指实足年龄较大但最高功能能力为5 - 7代谢当量的人,而“运动型”老年人的功能能力为9 - 10代谢当量,与实足年龄无关。与年轻时相比,脑重量减少约7%。在颞叶和纹状区,甚至有20 - 40%的细胞丢失,出现空泡和神经轴突变性,脂褐素积累。正常情况下脑组织血流量为50 - 60毫升/分钟/100克组织,随着生物年龄的增加,血流量降至约40毫升/分钟/100克组织。然而,这通常不是生物年龄的结果,而是疾病导致的。将65岁作为“老年期”开始的实足年龄是社会保障系统和政府组织为确定应发放福利的任意年龄而构建的社会政治概念。因此,它既不是一个界限,也不是在那个“年龄界限”时恰好发生标志老年的变化。在所谓衰老过程中,生物体的变化是因人而异的。所以,必须结合生物年龄,对生物体的身体和智力功能能力进行个体评估。

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