Lásiková S, Moravcová L, Pícha D, Horová B
1. Infekcní klinika FN Na Bulovce, Praha.
Epidemiol Mikrobiol Imunol. 2006 Apr;55(2):59-62.
West Nile virus (WNV) is a member of the Flaviviridae family, genus Flavivirus. Its reservoir hosts are wild birds. Infection is transmitted to humans by infected mosquitoes of the genus Culex. In most cases, it is either asymptomatic or manifests itself as mild fever. Typically, WNV illnesshas a sudden onset with fever above 39 degrees C and accompanying symptoms such as chills, headache, arthralgia, myalgia, back ache, cough and sore throat. Gastrointestinal symptoms are frequently reported. Generalized lymphadenopathy and conjunctivitis may develop. In some patients the infection can progress to meningoencephalitis. Diagnosis is currently based on detection of IgM antibodies in blood and cerebrospinal fluid or direct detection of WNV RNA.
西尼罗河病毒（WNV）是黄病毒科黄病毒属的成员。其储存宿主是野生鸟类。感染通过库蚊属受感染的蚊子传播给人类。在大多数情况下，它要么无症状，要么表现为轻度发热。通常，西尼罗河病毒病突然发作，体温超过39摄氏度，并伴有寒战、头痛、关节痛、肌痛、背痛、咳嗽和喉咙痛等症状。经常报告有胃肠道症状。可能会出现全身性淋巴结病和结膜炎。在一些患者中，感染可发展为脑膜脑炎。目前的诊断基于检测血液和脑脊液中的IgM抗体或直接检测西尼罗河病毒RNA。
