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[西尼罗河病毒引起的感染]

[Infections caused by West Nile virus].

作者信息

Hermanowska-Szpakowicz Teresa, Grygorczuk Sambor, Kondrusik Maciej, Zajkowska Joanna, Pancewicz Sławomir

机构信息

Klinika Chorób Zakaźnych i Neuroinfekcji Akademii Medycznej w Białymstoku.

出版信息

Przegl Epidemiol. 2006;60(1):93-8.

PMID:16758745
Abstract

West Nile virus (WNV) is a flavivirus related to tick-borne encephalitis virus endemic in northeast of Poland. WNV circulates among wild birds, transmitted by wide range of haematophagous arthropods. Several mosquito species, especially Culex spp., can transmit WNV to humans. WNV is responsible for a broad range of clinical symptoms, from asymptomatic infection to severe encephalitis and polio-like myelitis. Elderly persons are at especially high risk of death and severe neurological complications, with mortality among patients over 65 years old with WNV-related encephalitis being as high as 35%. Warm and humid climate favors the spread of WNV, however, it can also be effectively transmitted in moderate climate zones. During the last decade a worldwide spread of WNV was observed, with establishment of new enzootic foci and growing number of human cases. WNV seems to be already present in several European countries, including Poland. We describe detection of anti-WNV IgM antibodies in serum of patient with acute febrile infection, which may constitute the first case of confirmed WNV infection in Poland.

摘要

西尼罗河病毒(WNV)是一种黄病毒,与波兰东北部流行的蜱传脑炎病毒有关。WNV在野生鸟类中传播,由多种吸血节肢动物传播。几种蚊子,尤其是库蚊属,可将WNV传播给人类。WNV可导致广泛的临床症状,从无症状感染到严重脑炎和脊髓灰质炎样脊髓炎。老年人死亡和出现严重神经并发症的风险尤其高,65岁以上患有WNV相关脑炎的患者死亡率高达35%。温暖潮湿的气候有利于WNV的传播,不过,它也能在温带气候地区有效传播。在过去十年中,观察到WNV在全球范围内传播,出现了新的动物疫源地,人类病例数量不断增加。WNV似乎已在包括波兰在内的几个欧洲国家出现。我们描述了在一名急性发热感染患者血清中检测到抗WNV IgM抗体,这可能是波兰确诊的首例WNV感染病例。

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[Infections caused by West Nile virus].[西尼罗河病毒引起的感染]
Przegl Epidemiol. 2006;60(1):93-8.
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Persistence of West Nile Virus (WNV) IgM antibodies in cerebrospinal fluid from patients with CNS disease.西尼罗河病毒(WNV)IgM抗体在中枢神经系统疾病患者脑脊液中的持续存在情况。
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Acta Haematol Pol. 2013 Jul-Sep;44(3):284-293. doi: 10.1016/j.achaem.2013.07.022. Epub 2013 Jul 19.
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A Survey on West Nile and Usutu Viruses in Horses and Birds in Poland.波兰马和鸟类中西尼罗河病毒和乌舒图病毒的调查。
Viruses. 2018 Feb 17;10(2):87. doi: 10.3390/v10020087.
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Geographic variations of the bird-borne structural risk of West Nile virus circulation in Europe.欧洲西尼罗河病毒传播的鸟类传播结构风险的地理差异。
PLoS One. 2017 Oct 12;12(10):e0185962. doi: 10.1371/journal.pone.0185962. eCollection 2017.
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No evidence of West Nile virus infection among Polish patients with encephalitis.波兰脑炎患者中无西尼罗河病毒感染证据。
Cent Eur J Immunol. 2016;41(4):383-385. doi: 10.5114/ceji.2016.65137. Epub 2017 Jan 24.
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Occurrence of West Nile virus antibodies in wild birds, horses, and humans in Poland.波兰野生鸟类、马匹和人类中出现西尼罗河病毒抗体。
Biomed Res Int. 2015;2015:234181. doi: 10.1155/2015/234181. Epub 2015 Mar 19.