Chatterjee Justin S
Wound Healing Research Unit, Wales College of Medicine, Biology, Life and Health Sciences, Cardiff University, UK.
Int Wound J. 2005 Sep;2(3):258-65. doi: 10.1111/j.1742-4801.2005.00123.x.
Irrigation is a fundamental concept to the care of acute wounds and therefore of prime importance in all surgical specialties. A significant amount of research has been done in search of the most effective irrigation technique over the last three decades. There is evidence to show that irrigation is beneficial in the management of acute traumatic and elective wounds, but exactly which techniques and irrigation pressures needed for optimal outcome are still undetermined. A significant number of the studies to date lack the rigid scientific design needed in a climate of evidence-based medicine. There are substantial methodological flaws and a lack of standardisation between many studies hindering the ability to draw scientific conclusion and compare different studies. There are few randomised, controlled studies on human wounds, and extrapolation from animal studies must be done with caution. Investigation into different irrigation pressures for different levels of contamination is lacking. This would possibly produce a more logical approach for clinically managing acute wounds rather than a blanket treatment for all acute wounds irrespective of the level of contamination. Further research in this direction with greater attention to scientific methodology and design is needed.
冲洗是急性伤口护理的一个基本概念,因此在所有外科专业中都至关重要。在过去三十年里,为寻找最有效的冲洗技术已经开展了大量研究。有证据表明,冲洗在急性创伤性伤口和择期伤口的处理中是有益的,但究竟哪种技术和冲洗压力能实现最佳效果仍未确定。迄今为止,大量研究缺乏循证医学环境所需的严格科学设计。许多研究存在重大方法缺陷且缺乏标准化,这阻碍了得出科学结论和比较不同研究的能力。关于人体伤口的随机对照研究很少,必须谨慎地从动物研究进行推断。目前缺乏针对不同污染程度的不同冲洗压力的研究。这可能会产生一种更符合逻辑的临床处理急性伤口的方法,而不是对所有急性伤口不分污染程度一概而论地进行治疗。需要在这个方向上进行更多研究,并更加注重科学方法和设计。