Zhuang Yan, Yang Yin-mo, Wang Wei-min, Wang Hui-yuan, Wan Yuan-lian, Huang Yan-ting
Department of Surgery, First Hospital, Peking University, Beijing 100034, China.
Zhonghua Wai Ke Za Zhi. 2006 Jan 1;44(1):27-30.
To study the characters of chronic pancreatitis complicated by non-calculous obstructive jaundice, and discuss the methods for differentiation and treatment.
Twenty cases selected from January 1985 to December 2004 were analysed in the fields of differentiation and treatment.
All cases didn't present with typical clinical presentations and radiological features. Jaundice was presented as the main complaint. Stricture of the intra-pancreatic common bile duct was the symbolic radiological feature. Pancreatic disseminated inflammation was verified pathologically in these cases. CT, ultrasound, EUS, ERCP, MRCP and antigen-marker of neoplasm failed to offer the data for differentiation. The diagnosis could only be determined by pathological exam. The obstructive jaundice could be solved by biliary-enteric anastomoses successfully.
The patients with sole complaint of obstructive jaundice account for 15% of all inpatients with chronic pancreatitis. There exists a direct relationship between the jaundice and the pancreatic inflammation. This disorder should be differentiated from total pancreatic carcinoma, but few differentiated material could be offered by preoperative studies. Pathological result derived from the tissue sample obtained within the exploration would be reliable for diagnosis. The bypass between biliary tract and intestine would be a safe and economical treatment method.
研究慢性胰腺炎合并非结石性梗阻性黄疸的特点,探讨其鉴别与治疗方法。
对1985年1月至2004年12月选取的20例患者进行鉴别与治疗方面的分析。
所有病例均无典型临床表现及影像学特征。以黄疸为主要症状。胰内段胆总管狭窄为标志性影像学特征。经病理证实这些病例存在胰腺弥漫性炎症。CT、超声、内镜超声、内镜逆行胰胆管造影、磁共振胰胆管造影及肿瘤抗原标志物均无法提供鉴别数据。诊断只能通过病理检查确定。梗阻性黄疸可通过胆肠吻合成功解决。
以梗阻性黄疸为唯一症状的患者占慢性胰腺炎住院患者总数的15%。黄疸与胰腺炎症之间存在直接关系。该病症应与全胰腺癌相鉴别,但术前检查可提供的鉴别资料较少。术中获取组织样本的病理结果对诊断可靠。胆肠旁路术将是一种安全且经济的治疗方法。