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[犬对海马体电刺激形成工具性食物条件反射过程中的边缘内诱发电位]

[Intralimbic evoked potentials in the formation of an instrumental food conditioned reflex to hippocampal electrostimulation in dogs].

作者信息

Chilingarian L I, Grigor'ian G A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Sep-Oct;41(5):926-36.

PMID:1662443
Abstract

In dogs with the electrodes implanted in the hippocampus, amygdala, septum and hypothalamus an instrumental alimentary conditioned reflex (CR) was elaborated to electrostimulation of the hippocampus. Intralimbic evoked potentials (EPs) were studied during the elaboration and extinction of this reflex and during stimulations of limbic structures conducted with the purpose of CR generalization checking. Late EP components in the lateral hypothalamus and central nucleus of the amygdala changed during CR elaboration and extinction and in the hippocampus during amygdala testing. In both cases the amplitude of trace positivity and of slow negative wave was less, when during stimulation of the structure an instrumental movement was initiated than at its absence.

摘要

在电极植入海马体、杏仁核、隔区和下丘脑的犬只中,建立了一种操作性食物条件反射(CR),以对海马体进行电刺激。在该反射的建立和消退过程中,以及在为检查CR泛化而对边缘结构进行刺激的过程中,研究了边缘系统内诱发电位(EP)。在CR建立和消退过程中,下丘脑外侧和杏仁核中央核的晚期EP成分发生了变化,在杏仁核测试过程中,海马体中的晚期EP成分也发生了变化。在这两种情况下,当刺激该结构引发操作性动作时,痕迹正波和慢负波的振幅均小于未引发操作性动作时。

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