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[犬条件反射活动期间边缘脑结构的功能组织]

[Functional organization of limbic brain structures during conditioned reflex activity in the dog].

作者信息

Grigor'ian G A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1985 Nov-Dec;35(6):1053-61.

PMID:4090721
Abstract

In experiments on 3 dogs it was shown that instrumental defensive conditioned reflex (CR) to electrical stimulation of the hippocampus is generalized within the limbic system (LS). The rate of generalization depended on the place of testing stimuli in LS. Stimulation of the medial parts of LS at the stage of stabilized initial reflex did not produce the generalized CRs, while they appeared distinctly in response to stimulation of the lateral parts of LS. In the process of elaboration of heterogeneous CRs (defensive and alimentary) to electrical stimulation of the hippocampus, generalized conditioned reactions from some brain structures appeared in both situations to the same degree while from other structures--with considerable differences. These data point to a possible participation in the genesis of the generalized CRs both of signal and reinforcing brain mechanisms.

摘要

在对3只狗进行的实验中发现,对海马体进行电刺激所形成的工具性防御性条件反射(CR)在边缘系统(LS)内具有泛化性。泛化的速度取决于测试刺激在边缘系统中的位置。在初始反射稳定阶段,刺激边缘系统的内侧部分不会产生泛化的条件反射,而对边缘系统外侧部分的刺激则会明显出现泛化的条件反射。在对海马体进行电刺激以建立异质性条件反射(防御性和食物性)的过程中,某些脑结构的泛化性条件反应在两种情况下出现的程度相同,而其他结构的反应则存在显著差异。这些数据表明,信号和强化脑机制可能都参与了泛化性条件反射的产生。

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