Chilingarian L I, Grigor'ian G A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Sep-Oct;39(5):851-60.
Alimentary instrumental conditioned reflex (CR) was elaborated in dogs to light flashes (I series), electrostimulation (ES) of the hippocampus (II series) and the hypothalamus (III series). Nonreinforced ES of the hypothalamus, amygdala, hippocampus and septum reproduced pressings on the pedal to the least extent in the I series (17-40% of trials), increasing in the II-nd one up to 40-87% during stimulation of the lateral hypothalamus, medial amygdala and contralateral hippocampus. In the III-rd series the number of pressings increased statistically significantly in comparison with the I-st series for most structures. Probably, besides the artificial increase of motivation during ES of the limbic structures which took place in all series, in the II-nd and III-rd series significance for movement reproduction was acquired by CR generalization appearing due to close interconnection of the structures. In this phenomenon connections (evaluated by the EPs) from the tested structures to the initially signal one are important.
在犬身上建立了对闪光(I组)、海马体电刺激(ES,II组)和下丘脑电刺激(III组)的消化道工具性条件反射(CR)。下丘脑、杏仁核、海马体和隔区的非强化电刺激在I组中引起踏板按压的程度最低(占试验的17 - 40%),在II组中,刺激下丘脑外侧、杏仁核内侧和对侧海马体时,这一比例增加到40 - 87%。在III组中,与I组相比,大多数结构的按压次数在统计学上显著增加。可能,除了在所有组中都发生的边缘结构电刺激期间动机的人为增加外,在II组和III组中,由于结构之间的紧密相互连接而出现的CR泛化对运动再现具有重要意义。在这种现象中,从测试结构到最初的信号结构的连接(通过诱发电位评估)很重要。