Zavos Panayiotis M, Kaskar Khalied, Correa Juan R, Sikka Suresh C
Andrology Institute of America, P. O. Box 23777, Lexington, Kentucky 40523, USA.
Asian J Androl. 2006 May;8(3):337-41. doi: 10.1111/j.1745-7262.2006.00128.x.
To assess the seminal characteristics as well as the sexual behavior of men of various age groups to establish the presence of an aging effect on those characteristics.
Semen samples were collected from men (n = 792) undergoing in vitro fertilization or intrauterine insemination in cases of female factor infertility only. Samples were collected using a seminal collection device at intercourse and evaluated manually according to World Health Organization (WHO) standards. Men were divided into four groups according to their ages: (i) 20-30, (ii) 31-40, (iii) 41-50 and (iv) 51-60 years, and their seminal characteristics and responses to a sexual behavior questionnaire were compared.
The data showed statistically significant differences in the seminal characteristics tested, most notably in the sperm concentration, motility, grade of motility, hypo-osmotic swelling and normal sperm morphology. Furthermore, the decline in normal sperm morphology with age was more pronounced when using strict criteria rather than WHO standards. There were also differences in total sperm count, total motile sperm and total functional sperm fraction (assessed by both WHO and strict criteria). Significant differences were also observed in the sexual behavior patterns in older men in terms of the number of years they have been trying to conceive, sexual frequency and sexual satisfaction.
The data clearly illustrate an aging effect on semen characteristics and sexual behavior in men as they age. It is suggested that the aging effect be taken into consideration when proposing normal standard values for semen characteristics in routine semen analysis as outlined by WHO standards.
评估不同年龄组男性的精液特征及性行为，以确定年龄增长对这些特征是否存在影响。
仅在女性因素导致不孕的情况下，从接受体外受精或宫内人工授精的男性（n = 792）中采集精液样本。在性交时使用精液采集装置收集样本，并根据世界卫生组织（WHO）标准进行人工评估。根据年龄将男性分为四组：（i）20 - 30岁，（ii）31 - 40岁，（iii）41 - 50岁和（iv）51 - 60岁，并比较他们的精液特征以及对性行为问卷的回答。
数据显示，在所测试的精液特征方面存在统计学上的显著差异，最明显的是精子浓度、活力、活力等级、低渗肿胀和正常精子形态。此外，使用严格标准而非WHO标准时，正常精子形态随年龄的下降更为明显。总精子数、总活动精子数和总功能性精子比例（根据WHO标准和严格标准评估）也存在差异。在尝试受孕的年限、性交频率和性满意度方面，老年男性的性行为模式也存在显著差异。
数据清楚地表明，男性随着年龄增长，精液特征和性行为会受到年龄影响。建议在按照WHO标准进行常规精液分析时，提出精液特征正常标准值时考虑年龄影响。
