巴西珊瑚蛇（Micrurus）毒液的酶成分比较
Comparative enzymatic composition of Brazilian coral snake (Micrurus) venoms.
作者信息
Aird S D, da Silva N J
机构信息
Natural Product Sciences, Inc., Salt Lake City, UT 84108.
出版信息
Comp Biochem Physiol B. 1991;99(2):287-94. doi: 10.1016/0305-0491(91)90043-d.
PMID:1662592
Abstract
- Venoms of 11 coral snake taxa, including Micrurus albicinctus, M. corallinus, M. frontalis altirostris, M. f. brasiliensis, M. f. frontalis, M. fulvius fulvius, M. ibiboboca, M. lemniscatus ssp., M. randonianus, M. spixii spixii, and M. surinamensis surinamensis, were examined for 13 enzymatic activities. 2. These were compared with venoms of three outgroup taxa: Naja naja kaouthia, Bungarus multicinctus, and Bothrops moojeni. 3. Enzyme activity levels in Micrurus venoms were highly variable from species to species. 4. All venoms possessed phospholipase activity. 5. Protease activity against synthetic or dyed natural substrates was generally negligible in all elapid venoms examined. By contrast, most Micrurus venoms displayed ample L-leucine aminopeptidase activity. 6. Venom of M.s. surinamensis was significantly different from those of its congeners in most assays.
摘要
- 对11种珊瑚蛇分类群的毒液进行了13种酶活性检测，这些分类群包括白带珊瑚蛇、巴西珊瑚蛇、高鼻珊瑚蛇指名亚种、高鼻珊瑚蛇巴西亚种、高鼻珊瑚蛇指名亚种、佛罗里达珊瑚蛇指名亚种、伊比波博卡珊瑚蛇、彩纹珊瑚蛇亚种、兰多尼亚珊瑚蛇、斯皮克斯珊瑚蛇指名亚种和苏里南珊瑚蛇指名亚种。2. 将这些毒液与三个外群分类群的毒液进行比较：眼镜王蛇、银环蛇和矛头蝮。3. 珊瑚蛇毒液中的酶活性水平因物种而异，差异很大。4. 所有毒液都具有磷脂酶活性。5. 在所有检测的眼镜蛇科毒液中，针对合成或染色天然底物的蛋白酶活性通常可以忽略不计。相比之下，大多数珊瑚蛇毒液表现出充足的L-亮氨酸氨肽酶活性。6. 在大多数检测中，苏里南珊瑚蛇指名亚种的毒液与其同属其他种的毒液有显著差异。
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