Stamper Debra, Weissman Neil J, Brezinski Mark
Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, Massachusetts 02115, USA.
J Am Coll Cardiol. 2006 Apr 18;47(8 Suppl):C69-79. doi: 10.1016/j.jacc.2005.10.067.
The identification of unstable plaque is central in risk-stratifying patients for acute coronary events. Optical coherence tomography (OCT) is a recently introduced imaging modality that has shown considerable promise for the identification of high-risk plaques. Advantages of OCT include its high resolution (4 to 20 microm), high data acquisition rate, small and inexpensive guidewires/catheters, and ability to be combined with adjuvant optical techniques. This article summarizes the current state of intravascular OCT imaging, focusing on potential markers of instability and current limitations.
识别不稳定斑块是对急性冠脉事件患者进行风险分层的核心。光学相干断层扫描（OCT）是一种最近引入的成像方式，已显示出在识别高危斑块方面具有很大前景。OCT的优点包括其高分辨率（4至20微米）、高数据采集率、小型且廉价的导丝/导管，以及能够与辅助光学技术相结合。本文总结了血管内OCT成像的当前状态，重点关注不稳定性的潜在标志物和当前局限性。
