Yamanaka Kazuki, Nakayama Haruhiko, Watanabe Katsuya, Kameda Yoichi
Division of Thoracic Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Ann Thorac Surg. 2006 May;81(5):1904-6. doi: 10.1016/j.athoracsur.2005.07.081.
Thymic hyperplasia is a common feature in Graves' disease. However, in most cases, thymic enlargement is minimal, and radiologically detectable massive enlargement of the thymus is infrequently reported. Half of them undergo thymectomy due to the concern about a thymoma. We report a 28-year-old woman with untreated Graves' disease. She had an anterior mediastinal mass that was diagnosed as true thymic hyperplasia by biopsy and disappeared after treatment of the hyperthyroid state. Recognizing the association between thymic hyperplasia and Graves'disease, and existence of the benign course after treatment of the hyperthyroidism may be useful for avoiding unnecessary surgical procedure.
胸腺增生是Graves病的常见特征。然而，在大多数情况下，胸腺肿大程度轻微，放射学上可检测到的胸腺大量肿大鲜有报道。其中一半患者因担心胸腺瘤而接受胸腺切除术。我们报告一例28岁未治疗的Graves病女性患者。她有一个前纵隔肿块，活检诊断为真性胸腺增生，甲状腺功能亢进状态治疗后肿块消失。认识到胸腺增生与Graves病之间的关联，以及甲状腺功能亢进治疗后存在良性病程，可能有助于避免不必要的外科手术。
