Takami Koji, Omiya Hideyasu, Higashiyama Masahiko, Maeda Jun, Okami Jiro, Oda Kazuyuki, Tsujinaka Toshimasa, Kodama Ken
Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Ann Thorac Cardiovasc Surg. 2009 Dec;15(6):404-7.
A 32-year-old female case of large thymic hyperplasia with hyperthyroidism is reported. A computed tomography (CT) examination disclosed a large mediastinal mass (16 x 11 cm) with a heterogeneous internal structure containing both soft tissue density areas and fat density areas. The mass was histologically diagnosed as thymic lymphoid hyperplasia. The thymic mass enlarged during hyperthyroidism and then regressed markedly after treatment with antithyroid drugs. After the thymic mass decreased by about one third of its maximum volume, the mass stopped regressing and has remained the same size for more than 6 years. A CT scan showed a decrease in the soft tissue density area and predominance of the fat density area. The potential response to antithyroid therapy must be considered before recommending resection of thymic tumors diagnosed as hyperthyroidism-related thymic hyperplasia.
报告了一例32岁患有甲状腺功能亢进症的巨大胸腺增生女性病例。计算机断层扫描（CT）检查发现一个巨大的纵隔肿块（16×11厘米），其内部结构不均匀，包含软组织密度区域和脂肪密度区域。该肿块经组织学诊断为胸腺淋巴样增生。胸腺肿块在甲状腺功能亢进症期间增大，然后在使用抗甲状腺药物治疗后明显消退。在胸腺肿块缩小至最大体积的约三分之一后，肿块停止消退并在6年多的时间里一直保持相同大小。CT扫描显示软组织密度区域减小，脂肪密度区域占优势。在推荐切除诊断为与甲状腺功能亢进症相关的胸腺增生的胸腺肿瘤之前，必须考虑对抗甲状腺治疗的潜在反应。
