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儿童甲状腺功能亢进相关性胸腺肥大病例报告,表现为前纵隔肿块。

A case report of hyperthyroid-associated thymic hypertrophy in a child, presenting as an anterior mediastinal mass.

机构信息

University of Kentucky College of Medicine, Lexington, KY, USA.

出版信息

Eur J Pediatr. 2011 Jul;170(7):937-40. doi: 10.1007/s00431-011-1395-8. Epub 2011 Jan 28.

DOI:10.1007/s00431-011-1395-8
PMID:21274565
Abstract

We present the case of an 8-year-old boy with an anterior mediastinal mass and signs of hyperthyroidism. The anterior mediastinal mass had radiologic characteristics suggestive of thymic hypertrophy and regressed with antithyroid therapy. Though thymic hypertrophy is a known manifestation of hyperthyroidism, this is the youngest reported case. In selected cases, the diagnosis may be made based on the clinical picture, radiologic appearance, and response to antithyroid therapy without the need of a thymic biopsy or thymectomy.

摘要

我们报告了一例 8 岁男孩,其患有前纵隔肿块并伴有甲状腺功能亢进的征象。前纵隔肿块的影像学特征提示为胸腺肥大,并且随着抗甲状腺治疗而消退。尽管胸腺肥大是甲状腺功能亢进的已知表现,但这是报告的年龄最小的病例。在某些情况下,无需进行胸腺活检或胸腺切除术,根据临床表现、影像学表现和对抗甲状腺治疗的反应即可做出诊断。

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1
A case report of hyperthyroid-associated thymic hypertrophy in a child, presenting as an anterior mediastinal mass.儿童甲状腺功能亢进相关性胸腺肥大病例报告,表现为前纵隔肿块。
Eur J Pediatr. 2011 Jul;170(7):937-40. doi: 10.1007/s00431-011-1395-8. Epub 2011 Jan 28.
2
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本文引用的文献

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An adolescent with a mediastinal mass, diagnosed with Graves disease and thymic hyperplasia.一名患有格雷夫斯病和胸腺增生的纵隔肿块青少年患者。
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A case report of large thymic hyperplasia associated with hyperthyroidism.一例与甲状腺功能亢进相关的巨大胸腺增生病例报告。
Ann Thorac Cardiovasc Surg. 2009 Dec;15(6):404-7.
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Thymic hyperplasia presenting as anterior mediastinal mass in 2 patients with Graves disease.2例格雷夫斯病患者中表现为前纵隔肿块的胸腺增生。
Mayo Clin Proc. 2002 May;77(5):495-9. doi: 10.4065/77.5.495.
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Thymic enlargement in association with hyperthyroidism.胸腺肿大伴甲状腺功能亢进。
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