尽量减少早产儿呼吸机所致肺损伤
Minimising ventilator induced lung injury in preterm infants.
作者信息
Donn S M, Sinha S K
机构信息
Division of Neonatal-Perinatal Medicine, C S Mott Children's Hospital, 1500 E Medical Center Drive, Ann Arbor, MI, USA 48109-0254.
出版信息
Arch Dis Child Fetal Neonatal Ed. 2006 May;91(3):F226-30. doi: 10.1136/adc.2005.082271.
Abstract
Ventilator induced lung injury continues to occur at an unacceptably high rate, which is inversely related to gestational age. Although the "new BPD" may not be entirely avoidable in the extremely premature infant, recognition of risk factors and adoption of an appropriate ventilatory strategy, along with continuous real time monitoring, may help to minimise lung damage. This paper will review the pathogenesis of ventilator induced lung injury and strategies that may mitigate it.
摘要
呼吸机相关性肺损伤的发生率仍然高得令人难以接受，且与胎龄呈负相关。尽管在极早产儿中“新型支气管肺发育不良”可能无法完全避免，但识别危险因素、采用适当的通气策略以及持续实时监测，可能有助于将肺损伤降至最低。本文将综述呼吸机相关性肺损伤的发病机制以及可能减轻该损伤的策略。
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