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本文引用的文献

1
Volume-targeted versus pressure-limited ventilation in the neonate.新生儿容量靶向通气与压力限制通气的比较
Cochrane Database Syst Rev. 2005 Jul 20(3):CD003666. doi: 10.1002/14651858.CD003666.pub2.
2
Synchronized mechanical ventilation for respiratory support in newborn infants.同步机械通气用于新生儿呼吸支持
Cochrane Database Syst Rev. 2004 Oct 18(4):CD000456. doi: 10.1002/14651858.CD000456.pub2.
3
Invasive and noninvasive neonatal mechanical ventilation.有创和无创新生儿机械通气
Respir Care. 2003 Apr;48(4):426-39; discussion 439-41.
4
Clinical applications of pulmonary function and graphics.肺功能及相关图表的临床应用
Semin Neonatol. 2002 Oct;7(5):391-9. doi: 10.1053/siny.2002.0133.
5
Mechanisms of ventilator-induced lung injury in premature infants.早产儿呼吸机所致肺损伤的机制
Semin Neonatol. 2002 Oct;7(5):353-60. doi: 10.1053/siny.2002.0129.
6
High-frequency oscillatory ventilation to prevent bronchopulmonary dysplasia--are we there yet?高频振荡通气预防支气管肺发育不良——我们做到了吗？
N Engl J Med. 2002 Aug 29;347(9):682-4. doi: 10.1056/NEJMe020080.
7
High-frequency oscillatory ventilation versus conventional mechanical ventilation for very-low-birth-weight infants.高频振荡通气与传统机械通气用于极低出生体重儿的比较
N Engl J Med. 2002 Aug 29;347(9):643-52. doi: 10.1056/NEJMoa012750.
8
High-frequency oscillatory ventilation for the prevention of chronic lung disease of prematurity.高频振荡通气预防早产儿慢性肺病
N Engl J Med. 2002 Aug 29;347(9):633-42. doi: 10.1056/NEJMoa020432.
9
Update on patient-triggered ventilation.患者触发通气的最新进展。
Clin Perinatol. 2001 Sep;28(3):533-46. doi: 10.1016/s0095-5108(05)70105-6.
10
Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants.预防性与选择性使用表面活性剂预防早产儿发病和死亡的研究
Cochrane Database Syst Rev. 2001(2):CD000510. doi: 10.1002/14651858.CD000510.

尽量减少早产儿呼吸机所致肺损伤

Minimising ventilator induced lung injury in preterm infants.

作者信息

Donn S M, Sinha S K

机构信息

Division of Neonatal-Perinatal Medicine, C S Mott Children's Hospital, 1500 E Medical Center Drive, Ann Arbor, MI, USA 48109-0254.

出版信息

Arch Dis Child Fetal Neonatal Ed. 2006 May;91(3):F226-30. doi: 10.1136/adc.2005.082271.

DOI:10.1136/adc.2005.082271
PMID:16632652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2672704/
Abstract

Ventilator induced lung injury continues to occur at an unacceptably high rate, which is inversely related to gestational age. Although the "new BPD" may not be entirely avoidable in the extremely premature infant, recognition of risk factors and adoption of an appropriate ventilatory strategy, along with continuous real time monitoring, may help to minimise lung damage. This paper will review the pathogenesis of ventilator induced lung injury and strategies that may mitigate it.

摘要

呼吸机相关性肺损伤的发生率仍然高得令人难以接受，且与胎龄呈负相关。尽管在极早产儿中“新型支气管肺发育不良”可能无法完全避免，但识别危险因素、采用适当的通气策略以及持续实时监测，可能有助于将肺损伤降至最低。本文将综述呼吸机相关性肺损伤的发病机制以及可能减轻该损伤的策略。