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睡眠质量以及睡眠药物对慢性疼痛退伍军人的作用。

Sleep quality and the role of sleep medications for veterans with chronic pain.

作者信息

Chapman Judith B, Lehman Cassandra L, Elliott Janette, Clark J David

机构信息

Psychology Service--116B, Department of Veterans Affairs, Palo Alto Health Care System, 3801 Miranda Avenue, California 94304, USA.

出版信息

Pain Med. 2006 Mar-Apr;7(2):105-14. doi: 10.1111/j.1526-4637.2006.00110.x.

Abstract

OBJECTIVE

The purpose of this study was to investigate the nature of sleep problems in veterans presenting to a pain clinic, factors that predict likelihood of being prescribed a sleep medication, types of medications prescribed, and the relationships between sleep medication use and sleep quality, pain, and depression.

DESIGN/SETTING/PATIENTS: Participants were 201 consecutive patients referred to a Veterans Affairs outpatient pain clinic. They were administered the Pittsburgh Sleep Quality Index, Multidimensional Pain Inventory, and Beck Depression Inventory at intake and 2-month follow-up. Sleep and opioid medication prescriptions were also monitored.

RESULTS

Pain severity did not predict global sleep quality; global sleep quality was not predictive of pain severity. Greater depression predicted both more severe pain and more sleep impairment. Having previously been prescribed such medications was the only significant predictor of being prescribed a sleep medication at the time of the 2-month assessment. For the 45% of participants on sleep medications, these medications were not associated with any significant change in pain factors or depression. However, sleep medication use was associated with worse global sleep quality, sleep duration, and sleep efficiency. Opioid prescription was not a significant predictor of sleep factors, pain-related variables, or depression symptoms.

DISCUSSION

Results suggest depression may contribute more significantly to sleep problems than pain-related variables in this population. The data suggest the need for controlled, prospective studies of sleep medication to further investigate the impact of sleep medications on sleep components in patients with chronic pain.

摘要

目的

本研究旨在调查前往疼痛诊所就诊的退伍军人睡眠问题的性质、预测开具睡眠药物可能性的因素、所开具药物的类型,以及睡眠药物使用与睡眠质量、疼痛和抑郁之间的关系。

设计/地点/患者:研究对象为连续201名转诊至退伍军人事务部门诊疼痛诊所的患者。在患者就诊时及2个月随访时,对他们进行匹兹堡睡眠质量指数、多维疼痛量表和贝克抑郁量表评估。同时监测睡眠和阿片类药物处方情况。

结果

疼痛严重程度不能预测总体睡眠质量;总体睡眠质量也不能预测疼痛严重程度。抑郁程度越高,疼痛越严重,睡眠障碍也越严重。在2个月评估时,之前曾开具过此类药物是开具睡眠药物的唯一显著预测因素。对于45%服用睡眠药物的参与者来说,这些药物与疼痛因素或抑郁的任何显著变化均无关联。然而,使用睡眠药物与总体睡眠质量较差、睡眠时间较短和睡眠效率较低有关。阿片类药物处方不是睡眠因素、疼痛相关变量或抑郁症状的显著预测因素。

讨论

结果表明,在该人群中,抑郁对睡眠问题的影响可能比疼痛相关变量更为显著。数据表明,需要对睡眠药物进行对照前瞻性研究,以进一步调查睡眠药物对慢性疼痛患者睡眠成分的影响。

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