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小儿高血糖高渗综合征:诊断困难与高死亡率

Pediatric hyperglycemic hyperosmolar syndrome: diagnostic difficulties and high mortality rate.

作者信息

Cochran Joel B, Walters Scott, Losek Joseph D

机构信息

Pediatric Department, Medical University of South Carolina, Charleston, SC 29425, USA.

出版信息

Am J Emerg Med. 2006 May;24(3):297-301. doi: 10.1016/j.ajem.2005.10.007.

Abstract

Childhood obesity has become a pandemic health care problem. A complication of childhood obesity is type 2 diabetes mellitus which has increased 10-fold in the past 20 years. A serious complication of type 2 diabetes mellitus is hyperglycemic hyperosmolar syndrome (HHS). The following case is an obese adolescent boy with a newly diagnosed HHS. The demographic and clinical characteristics of our case and those of 17 other cases from recently published small case series are presented. Of the 18 cases, there were 13 deaths (72%). The purpose of this report and literature review is to emphasize the importance of early diagnoses and treatment of pediatric HHS.

摘要

儿童肥胖已成为一个全球性的医疗保健问题。儿童肥胖的一个并发症是2型糖尿病,在过去20年中其发病率增长了10倍。2型糖尿病的一个严重并发症是高血糖高渗综合征(HHS)。以下病例是一名肥胖青少年男性,新诊断为HHS。本文介绍了该病例以及最近发表的小病例系列中其他17例病例的人口统计学和临床特征。18例病例中,有13例死亡(72%)。本报告及文献综述的目的是强调儿童HHS早期诊断和治疗的重要性。

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