Mezvrishvili Z, Managadze L
National Centre of Urology, Tbilisi, Georgia.
Georgian Med News. 2006 Mar(132):20-3.
Nerve sparing retroperitoneal lymph node dissection is standard treatment method for early stage non-seminomatous germ cell tumor. However, an alternative approaches (surveillance policy, adjuvant and primary chemotherapy) have approximately the same capability for cure. Therefore, the current debate is to decide which is less morbid for the patient at risk. We assessed associated complications of nerve sparing retroperitoneal lymph node dissection in 33 patients (25 with clinical stage I and 8 with clinical stage IIA) treated at our center from June 1996 to November 2005. There were 7 (21%) complications (2 intraoperative, 4 early minor and 1 early major) in 6 out of the 33 operated patients. There were no late complications. Antegrade ejaculation was preserved in 30 patients (91%). Postoperatively 19 out of 33 patients were classified as pathological stage I and 14 as pathological stage IIA. Both groups were balanced with respect to distribution of complications. The data indicate that nerve sparing RPLND is a well tolerated urologic procedure with a low early and no late morbidity.
保留神经的腹膜后淋巴结清扫术是早期非精原细胞性生殖细胞肿瘤的标准治疗方法。然而,其他替代方法(监测策略、辅助化疗和一线化疗)具有大致相同的治愈能力。因此,当前的争论在于确定哪种方法对有风险的患者造成的伤害更小。我们评估了1996年6月至2005年11月在我们中心接受治疗的33例患者(25例临床I期和8例临床IIA期)保留神经的腹膜后淋巴结清扫术的相关并发症。33例接受手术的患者中有6例出现了7例(21%)并发症(2例术中并发症、4例早期轻微并发症和1例早期严重并发症)。无晚期并发症。30例患者(91%)保留了顺行射精功能。术后33例患者中19例被分类为病理I期,14例为病理IIA期。两组在并发症分布方面是均衡的。数据表明,保留神经的腹膜后淋巴结清扫术是一种耐受性良好的泌尿外科手术,早期发病率低且无晚期发病率。