Caricato Marco, Borzomati Domenico, Ausania Fabio, Garberini Andrea, Rabitti Carla, Tonini Giuseppe, Coppola Roberto
Department of General Surgery, Campus Bio-Medico University, Rome, Italy.
Pancreatology. 2006;6(4):306-8. doi: 10.1159/000092693. Epub 2006 Apr 19.
The first discovery of a cerebellar metastasis of pancreatic carcinoma in a living patient is described. Two years earlier the patient had undergone a pancreaticoduodenectomy for an adenocarcinoma of the head of the pancreas with a lymph node metastasis. After complete surgical removal of the tumor, he underwent adjuvant chemoradiation. Two years later the patient presented with intractable vomiting, which was attributed to peritoneal carcinomatosis. Clinical evaluation revealed an intracranial tumor without signs of pancreatic recurrence. The tumor was surgically removed. One year later the patient developed multiple brain metastases and he is currently undergoing gemcitabine-based chemotherapy.
本文描述了首例在活体患者中发现的胰腺癌小脑转移病例。两年前，该患者因胰头腺癌伴淋巴结转移接受了胰十二指肠切除术。肿瘤完全切除后，他接受了辅助放化疗。两年后，患者出现顽固性呕吐，原因是腹膜癌转移。临床评估发现颅内有肿瘤，无胰腺复发迹象。肿瘤通过手术切除。一年后，患者出现多处脑转移，目前正在接受以吉西他滨为基础的化疗。
