Osorio-de-Castro Claudia Garcia Serpa, Pepe Vera Lucia Edais, Luiza Vera Lucia, Cosendey Marly Aparecida Elias, Freitas Aline Matias de, Miranda Frederico Fonseca, Bermudez Jorge Antonio Zepeda, Leal Maria do Carmo
Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Cad Saude Publica. 2004;20 Suppl 1:S73-82. doi: 10.1590/s0102-311x2004000700008. Epub 2004 May 20.
Few studies describe drug utilization in pregnancy focusing on prescribing practices. This study is part of a larger survey on perinatal care in the City of Rio de Janeiro, Brazil. The type of hospital (public, contracted out by the Unified National Health System, or private) determined the stratification of 10,072 hospitalized post-partum women, who were asked about medication used during pregnancy. Hospital records supplied information on drugs prescribed during labor. Drugs were classified according to the Anatomical Therapeutic Chemical (ATC) system. Another system was used for specific cases of referred use. A mean of 2.08 drugs was prescribed during labor, and a mean of 2.3 was reported during pregnancy. Anesthetics, antibiotics, oxytocin, and analgesics were the most frequently prescribed during labor, with significant differences between strata. Ferrous sulfate, vitamins, scopolamine, and acetaminophen were the main drugs reported during pregnancy. Women who had attempted abortion referred use of various kinds of tea (49.7%) and misoprostol (9.2%). The drug utilization pattern was consistent with the literature. This study offers knowledge on prescribing patterns during labor and self-reported use during pregnancy in both the public and private sectors.
很少有研究关注孕期药物使用情况并聚焦于处方开具行为。本研究是巴西里约热内卢市一项关于围产期护理的大型调查的一部分。医院类型（公立、由统一国家卫生系统外包或私立）决定了对10072名住院产后妇女的分层，这些妇女被问及孕期所用药物。医院记录提供了分娩期间开具药物的信息。药物根据解剖治疗化学（ATC）系统进行分类。对于特定的参考使用情况则采用另一种系统。分娩期间平均开具2.08种药物，孕期报告的平均用药种类为2.3种。麻醉药、抗生素、催产素和镇痛药是分娩期间最常开具的药物，各层之间存在显著差异。硫酸亚铁、维生素、东莨菪碱和对乙酰氨基酚是孕期报告的主要药物。曾尝试堕胎的妇女提及使用各种茶（49.7%）和米索前列醇（9.2%）。药物使用模式与文献一致。本研究提供了关于公立和私立部门分娩期间处方开具模式以及孕期自我报告用药情况的知识。
