Sendur O Faruk, Gurer Gulcan, Bozbas Gulnur Tasci
Department of Physical Medicine and Rehabilitation, Adnan Menderes University Medical School Hospital, Aydin 09100, Turkey.
Clin Rheumatol. 2007 Apr;26(4):485-7. doi: 10.1007/s10067-006-0304-4. Epub 2006 Apr 25.
The etiology and pathogenic mechanisms of fibromyalgia (FM) are unknown. A number of studies have suggested that there was a link between hypermobility and FM. In this study, we aimed to expose the frequency of hypermobility in FM patients and its relation with clinical findings. For this reason, 236 women (118 FM women as study group and 118 healthy women as control group) were enrolled in the study. Joint hypermobility was evaluated in the participants by using Beighton scoring system. The rate of joint hypermobility among FM patients (Beighton score of at least 4 or more) was found to be higher than the control group (46.6 vs 28.8%). This result was also statistically meaningful (p<0.05). In addition, the mean Beighton score of FM group was observed to be higher than the control (3.68 vs 2.55, p<0.001). Although not reaching statistical difference (p>0.05), more severe clinical findings were observed in FM patients with hypermobility when compared with ones without.
纤维肌痛（FM）的病因和发病机制尚不清楚。多项研究表明，关节活动过度与FM之间存在联系。在本研究中，我们旨在揭示FM患者关节活动过度的频率及其与临床症状的关系。因此，本研究纳入了236名女性（118名FM女性作为研究组，118名健康女性作为对照组）。采用Beighton评分系统对参与者的关节活动过度情况进行评估。发现FM患者中关节活动过度的发生率（Beighton评分至少为4分或更高）高于对照组（46.6%对28.8%）。这一结果在统计学上也具有显著意义（p<0.05）。此外，观察到FM组的平均Beighton评分高于对照组（3.68对2.55，p<0.001）。与无关节活动过度的FM患者相比，有关节活动过度的FM患者临床症状更严重，尽管未达到统计学差异（p>0.05）。
