McCarthy R N, Jeffcott L B, Funder J W, Fullerton M, Clarke I J
Department of Veterinary Science, University of Melbourne, Victoria.
Aust Vet J. 1991 Nov;68(11):359-61. doi: 10.1111/j.1751-0813.1991.tb00736.x.
A controlled period of submaximal exercise on a treadmill was used as a standardised stress test in 6 young horses to monitor the effects of training. Circulating plasma concentrations of immunoreactive beta-endorphin (IR beta-EP) were measured before, during and after the exercise period. The stress test was conducted on 3 occasions during an intensive training program lasting 14 weeks. In week 3 a marked increase in plasma IR beta-EP (P = 0.003) was demonstrated as a result of training, but by the last exercise test performed in week 9 no significant increase in plasma IR beta-EP concentrations could be detected. During the training period the basal concentrations of plasma IR beta-EP significantly decreased (P = 0.0059). Plasma adrenocorticotrophin (ACTH) did not increase during exercise, although there was a trend of decreasing basal plasma ACTH by the end of the training period. It was concluded that a standardised work test acted as a mild stress to unfit horses, but as the horses' fitness increased the hormonal response to exercise diminished. Basal plasma beta-EP concentrations were decreased with increasing fitness.
在6匹年轻马匹中，采用在跑步机上进行亚极量运动的可控时间段作为标准化应激试验，以监测训练效果。在运动期之前、期间和之后测量循环血浆中免疫反应性β-内啡肽（IRβ-EP）的浓度。在为期14周的强化训练计划中，应激试验进行了3次。在第3周，由于训练，血浆IRβ-EP显著增加（P = 0.003），但在第9周进行的最后一次运动试验中，未检测到血浆IRβ-EP浓度有显著增加。在训练期间，血浆IRβ-EP的基础浓度显著降低（P = 0.0059）。运动期间血浆促肾上腺皮质激素（ACTH）没有增加，尽管在训练期结束时基础血浆ACTH有下降趋势。得出的结论是，标准化工作试验对不适应的马匹起到轻度应激作用，但随着马匹适应性增加，对运动的激素反应减弱。基础血浆β-EP浓度随着适应性增加而降低。
