Campbell Rona, Mills Nicola, Sanford Emma, Graham Anna, Low Nicola, Peters Tim J
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol BS8 2PR, UK.
BMC Public Health. 2006 Apr 25;6:106. doi: 10.1186/1471-2458-6-106.
The advent of urine testing for Chlamydia trachomatis has raised the possibility of large-scale screening for this sexually transmitted infection, which is now the most common in the United Kingdom. The purpose of this study was to investigate the effect of an invitation to be screened for chlamydia and of receiving a negative result on levels of anxiety, depression and self-esteem.
19,773 men and women aged 16 to 39 years, selected at random from 27 general practices in two large city areas (Bristol and Birmingham) were invited by post to send home-collected urine samples or vulvo-vaginal swabs for chlamydia testing. Questionnaires enquiring about anxiety, depression and self-esteem were sent to random samples of those offered screening: one month before the dispatch of invitations; when participants returned samples; and after receiving a negative result.
Home screening was associated with an overall reduction in anxiety scores. An invitation to participate did not increase anxiety levels. Anxiety scores in men were lower after receiving the invitation than at baseline. Amongst women anxiety was reduced after receipt of negative test results. Neither depression nor self-esteem scores were affected by screening.
Postal screening for chlamydia does not appear to have a negative impact on overall psychological well-being and can lead to a decrease in anxiety levels among respondents. There is, however, a clear difference between men and women in when this reduction occurs.
针对沙眼衣原体的尿液检测方法的出现,增加了对这种性传播感染进行大规模筛查的可能性,目前沙眼衣原体感染在英国最为常见。本研究的目的是调查衣原体筛查邀请以及收到阴性检测结果对焦虑、抑郁和自尊水平的影响。
从两个大城市地区(布里斯托尔和伯明翰)的27家普通诊所中随机选取19773名年龄在16至39岁之间的男性和女性,通过邮寄方式邀请他们将在家采集的尿液样本或外阴阴道拭子寄回用于衣原体检测。在邀请发出前一个月、参与者寄回样本时以及收到阴性结果后,向被邀请参加筛查的随机样本发放询问焦虑、抑郁和自尊情况的问卷。
家庭筛查与焦虑得分的总体降低相关。参与邀请并未增加焦虑水平。男性在收到邀请后的焦虑得分低于基线水平。在女性中,收到阴性检测结果后焦虑有所减轻。抑郁和自尊得分均未受到筛查的影响。
衣原体的邮寄筛查似乎对整体心理健康没有负面影响,并且可以导致受访者焦虑水平的降低。然而,这种降低在男性和女性中出现的时间存在明显差异。