Langelaan Maaike, Wouters Bill, Moll Annette C, de Boer Michiel R, van Rens Ger H M B
Department of Ophthalmology, VU University Medical Centre, Amsterdam, The Netherlands.
Invest Ophthalmol Vis Sci. 2006 May;47(5):1817-23. doi: 10.1167/iovs.04-1345.
To investigate the underestimation of field loss in functional field score (FFS) between the Goldmann isopters III-4e and V-4e in visually impaired patients, in order to develop a predictive model for the FFS(III-4e) based on FFS(v-4e) that adjusts for possible confounders. Although the visual field is generally evaluated using Goldmann isopter III-4e, it has the disadvantage that not all low-vision patients are able to see the stimulus corresponding to this isopter.
Goldmann visual fields were obtained from 58 patients with a variety of eye diseases. Eligibility criteria were age of 18 years or older and valid results of a Goldmann III-4e and V-4e visual field test in at least one eye. Linear regression was used to develop the model, setting FFS(III-4e) as the dependent variable and FFS(V-4e) as the independent one.
The FFS(V-4e) was higher than the FFS(III-4e), the mean difference being 14.56 points (95% CI, 12.48 -16.64). Multiple linear regression analysis showed that age, functional acuity score, primary eye disease, and central-peripheral loss were not confounders for the prediction of FFS(III-4e). FFS(III-4e) was estimated with the following equation: FFS(III-4e) = -19.25 + 1.063 x FFS(V-4e).
The relationship between FFS(III-4e) and FFS(V-4e) is linear, and the FFS(V-4e) can be used to estimate the FFS(III-4e). In practice, just subtracting 19.25 points of the value of FFS(V-4e) will be sufficient to estimate the value of FFS(III-4e). This model should give confidence about using the bigger isopter for determining the visual impairment of a person by the FFS.
研究在视力受损患者中,戈德曼视野计III - 4e和V - 4e之间功能视野评分(FFS)中视野缺损的低估情况,以便基于FFS(V - 4e)建立一个针对FFS(III - 4e)的预测模型,并对可能的混杂因素进行校正。尽管通常使用戈德曼视野计III - 4e来评估视野,但它存在一个缺点,即并非所有低视力患者都能看到与此视野计对应的刺激。
从58例患有各种眼部疾病的患者中获取戈德曼视野检查结果。纳入标准为年龄在18岁及以上,且至少一只眼睛的戈德曼III - 4e和V - 4e视野测试结果有效。使用线性回归建立模型,将FFS(III - 4e)作为因变量,FFS(V - 4e)作为自变量。
FFS(V - 4e)高于FFS(III - 4e),平均差值为14.56分(95%置信区间,12.48 - 16.64)。多元线性回归分析表明,年龄、功能视力评分、原发性眼病和中央 - 周边视野缺损并非预测FFS(III - 4e)的混杂因素。FFS(III - 4e)通过以下公式估算:FFS(III - 4e)= -19.25 + 1.063×FFS(V - 4e)。
FFS(III - 4e)与FFS(V - 4e)之间的关系是线性的,FFS(V - 4e)可用于估算FFS(III - 4e)。在实际应用中,只需从FFS(V - 4e)的值中减去19.25分,就足以估算FFS(III - 4e)的值。该模型应为通过FFS使用更大的视野计来确定一个人的视力损害提供信心。