Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
PLoS One. 2018 Sep 13;13(9):e0203258. doi: 10.1371/journal.pone.0203258. eCollection 2018.
To compare the Esterman Disability Score (EDS) obtained with Goldmann perimetry (GP) testing and the Humphrey field analyzer (HFA) in low vision Japanese subjects. Subjects were also divided into groups by diagnosis to examine how disease influences EDS measurements.
The EDS was obtained using GP (GP-EDS) and the built-in testing program of the HFA (HFA-EDS). Tests were performed within 3 months of each other. Regression analyses were used to examine the relationship between GP-EDS and HFA-EDS.
A total of 128 visually impaired subjects were included in this study. Subjects had low vision because of glaucoma (57 subjects), age-related macular degeneration (AMD, 17 subjects), retinitis pigmentosa (RP, 17 subjects), and other causes (37 subjects). The GP-EDS obtained was well-correlated with HFA-EDS (r = 0.87, P < 0.001) and it was possible to estimate HFA-EDS from GP-EDS. The GP-EDS was significantly lower than the HFA-EDS in eyes with glaucoma and RP. There was no significant difference between EDS values in eyes with AMD or other disease.
The GP-EDS correlated well with the HFA-EDS. However, the relationship between the EDS measured with the two different testing modalities varies by disease.
比较在低视力日本受试者中使用 Goldmann 视野计 (GP) 测试和 Humphrey 视野分析仪 (HFA) 获得的 Esterman 失能评分 (EDS)。还根据诊断将受试者分为不同组,以检查疾病如何影响 EDS 测量。
使用 GP (GP-EDS) 和 HFA 的内置测试程序 (HFA-EDS) 获得 EDS。两次测试在彼此 3 个月内进行。回归分析用于检查 GP-EDS 和 HFA-EDS 之间的关系。
本研究共纳入 128 名视力受损受试者。受试者因青光眼 (57 名受试者)、年龄相关性黄斑变性 (AMD,17 名受试者)、色素性视网膜炎 (RP,17 名受试者) 和其他原因 (37 名受试者) 而视力低下。获得的 GP-EDS 与 HFA-EDS 高度相关 (r = 0.87,P < 0.001),并且可以从 GP-EDS 估计 HFA-EDS。青光眼和 RP 眼的 GP-EDS 明显低于 HFA-EDS。AMD 或其他疾病眼的 EDS 值无显著差异。
GP-EDS 与 HFA-EDS 相关性良好。然而,两种不同测试模式测量的 EDS 之间的关系因疾病而异。