Furukawa T
Res Commun Chem Pathol Pharmacol. 1975 Mar;10(3):554-8.
Human lymphoid cells transformed by Epstein-Barr (EB) virus are thought to be B-lymphocytes. Transformation of human mononuclear leukocytes by Epstein-Barr virus was decreased or lost by removing adhering or nonadhering mononuclear cells from the mixtures of peripheral blood leukocytes but was not decreased by removing T-lymphocytes. Recombining adherent and nonadherent mononuclear cells without T-lymphocytes restored transformability, but conditioned medium from cultures of adherent cells did not. Cooperation between non-adherent (B-cells) and adherent cells (monocytes) is necessary for EB virus transformation.
被爱泼斯坦 - 巴尔（EB）病毒转化的人类淋巴细胞被认为是B淋巴细胞。通过从外周血白细胞混合物中去除贴壁或非贴壁单核细胞，爱泼斯坦 - 巴尔病毒对人类单核白细胞的转化作用降低或丧失，但去除T淋巴细胞并不会降低这种转化作用。将不含T淋巴细胞的贴壁和非贴壁单核细胞重新组合可恢复转化能力，但来自贴壁细胞培养物的条件培养基却不能。EB病毒转化需要非贴壁（B细胞）和贴壁细胞（单核细胞）之间的合作。
